Colella G, Vuolo G, Siniscalchi G, Moscariello A, Itro A
Department of Head and Neck Pathology, Oral Cavity and Audio-Verbal Communication, Faculty of Medicine and Surgery, Second University of Naples, Naples, Italy.
Minerva Stomatol. 2005 Sep;54(9):509-16.
Vascular maxillo-facial malformations, common pathologies in children, represent 7% of all benign tumors. They are divided into vascular malformations and hemangiomas. In the 70s-80s radiotherapy was the most applied technique, but because of its misuse or overdose, it could lead to relevant and hard consequences for the impact on the salivar glands, periodontium and growing maxillo-facial nuclei. The authors describe the case of a 38-year-old man, who, during infancy, was submitted to radiotherapy for a hemangioma to his chin and cheek. He was under observation for an agressive periodontitis, followed by a serious facial asimmetry, located in his irradiated side. They describe the therapy and the results obtained, underlying the particular difficulties detected in operating on tissues hardly and often irreversibly injured by radiotherapy. On the basis of this clinical case and of the most up-dated knowledge, therapeutical alternatives such as embolization, cryotherapy, cortisonic systemic and intralesional therapy, the use of interferon gamma 2 and the use of the most recent laser, are analyzed, and advantages and disadvantages and the most appropriate indications are underlined.
颌面部血管畸形是儿童常见的病理情况，占所有良性肿瘤的7%。它们分为血管畸形和血管瘤。在20世纪70年代至80年代，放射治疗是最常用的技术，但由于其使用不当或剂量过大，可能会对唾液腺、牙周组织和生长中的颌面部核产生相关且严重的后果。作者描述了一名38岁男性的病例，该男性在婴儿期因下巴和脸颊的血管瘤接受了放射治疗。他因侵袭性牙周炎接受观察，随后出现严重的面部不对称，位于接受放疗的一侧。他们描述了治疗方法和取得的结果，强调了在对因放疗而严重且往往不可逆转受损的组织进行手术时发现的特殊困难。基于这一临床病例和最新知识，分析了栓塞、冷冻疗法、皮质类固醇全身和病灶内治疗、使用干扰素γ-2以及使用最新激光等治疗选择，并强调了其优缺点和最合适的适应症。
