Lockwood A, Hope-Ross M, Chell P
Birmingham and Midland Eye Centre, City Hospital, Birmingham, UK.
Eye (Lond). 2006 Jul;20(7):837-9. doi: 10.1038/sj.eye.6702053. Epub 2005 Oct 7.
Diabetes mellitus is frequently associated with microvascular complications such as retinopathy, nephropathy, and peripheral neuropathy. Neurotrophic keratopathy occurs in response to a neuropathy of the ophthalmic division of the trigeminal nerve. Rarely has diabetic neurotrophic keratopathy been described. This paper discusses the ophthalmic histories of three patients who presented with diabetic neurotrophic keratopathy. In one patient the corneal ulceration was the sole presenting feature of his diabetes. We discuss the need for increased vigilance in the ophthalmic community for suspecting diabetes in patients with unexplained corneal epithelial disease.
糖尿病常与微血管并发症相关，如视网膜病变、肾病和周围神经病变。神经营养性角膜病变是由三叉神经眼支神经病变引起的。糖尿病性神经营养性角膜病变很少被描述。本文讨论了三名患有糖尿病性神经营养性角膜病变患者的眼科病史。在一名患者中，角膜溃疡是其糖尿病的唯一表现特征。我们讨论了眼科界对于不明原因角膜上皮疾病患者怀疑患有糖尿病时提高警惕的必要性。
