Le Goarant de Tromelin J, Deruelle P, Lucot J-P, Collinet P, Cosson M, Vinatier D
Clinique de gynécologie et d'obstétrique, hôpital Jeanne-de-Flandre, CHRU de Lille, 1, rue Eugène-Avinée, 59037 Lille cedex, France.
Gynecol Obstet Fertil. 2005 Sep;33(9):594-9. doi: 10.1016/j.gyobfe.2005.07.018.
Ovarian immature teratoma is a malignant germ cell tumor and represents less than 1% of ovarian malignant tumors. Tissues are derived from the three germ layers (endo-, meso- and ectoderm). Tumor grading is based on the amount of immature neuroepithelium present. The prognosis is directly correlated to histologic grade. Rapid growth leads to large tumors with an early diagnosis. Therapeutic management is balanced between adjuvant chemotherapy and surgery alone. Nevertheless, as immature teratoma mostly occurs in young women, the main objective is to preserve fertility.
卵巢未成熟畸胎瘤是一种恶性生殖细胞肿瘤,占卵巢恶性肿瘤的比例不到1%。组织来源于三个胚层(内胚层、中胚层和外胚层)。肿瘤分级基于未成熟神经上皮的数量。预后与组织学分级直接相关。快速生长导致肿瘤较大且诊断较早。治疗管理在辅助化疗和单纯手术之间取得平衡。然而,由于未成熟畸胎瘤大多发生在年轻女性中,主要目标是保留生育能力。