Takase Yasushi
Department of Neurology, Toyonaka Municipal Hospital.
Nihon Rinsho. 2005 Oct;63(10):1747-52.
Cluster headaches are characterized by attacks of strictly unilateral severe pain which is orbital, supraorbital, temporal or in any combination of these sites associated with one or more of the following, ipsilateral conjunctival injection, lacrimation, nasal congestion, rhinorrhea, forehead and facial sweating, miosis, ptosis, and eyelid edema. Most patients are usually unable to lie down, restless or agitated during an attack. The attacks last 15-180 minutes and occur from once every other day to 8 times a day. Cluster periods usually last for weeks or months separated by remission periods, however about 10-15% of patients have chronic symptoms without remission. Age at onset is usually 20-40 years and prevalence is 3-4 times higher in men than in women. Acute attacks involve activation of the posterior hypothalamic gray matter. Pharmacological treatment for cluster headache can be abortive, prophylactic, or a combination of both methods.
丛集性头痛的特点是发作时出现严格单侧的剧痛，疼痛位于眼眶、眶上、颞部或这些部位的任意组合，并伴有以下一种或多种症状：同侧结膜充血、流泪、鼻充血、流涕、前额和面部出汗、瞳孔缩小、上睑下垂和眼睑水肿。大多数患者在发作期间通常无法躺下，烦躁不安或激动。发作持续15 - 180分钟，发作频率为每隔一天一次至每天8次。丛集期通常持续数周或数月，期间有缓解期，然而约10 - 15%的患者有慢性症状且无缓解。发病年龄通常在20 - 40岁，男性患病率比女性高3 - 4倍。急性发作涉及下丘脑后部灰质的激活。丛集性头痛的药物治疗可以是终止发作、预防性治疗或两种方法的联合使用。
