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食管胃吻合术后颈段吻合口瘘累及纵隔或胸腔的诊治:附5例报告并文献复习

[Diagnosis and treatment of cervical anastomotic fistula contaminating mediastinum or pleural cavity after esophagogastrostomy: a report of five cases with literature review].

作者信息

Chen Gang, Xie Liang, Tang Ji-Ming, Ben Xiao-Song, Yang Xue-Ning

机构信息

Department of Thoracic Surgery, Guangdong Provincial People's Hospital, Guangzhou, Guangdong, P. R. China.

出版信息

Ai Zheng. 2005 Oct;24(10):1280-3.

Abstract

BACKGROUND & OBJECTIVE: A special kind of fistula will be formed when cervical gastroesophageal anastomotic fistula occurs and its contents contaminate mediastinum or pleural cavity after esophagogastrostomy. The diagnosis and treatment are difficult to made. It is very dangerous if the treatment is incorrect. This study was to analyze the causes, preventive measures, diagnosis methods and standard, and appropriate treatments of this kind of fistula.

METHODS

Clinical data of 5 patients who suffered cervical anastomotic fistula contaminating mediastinum or pleural cavity after esophagogastrostomy, treated in our hospital, were retrospectively analyzed; the related literature was reviewed.

RESULTS

The morbidity of this kind fistula was 1.83%(4/219) in our hospital. All the 5 patients suffered fistula 1-13 days after esophagogastrostomy; bronchopleural fistula occurred in 2 patients. The main causes of this kind of anastomotic fistula were hypertensive anastomosis, low anastomotic location, incomplete suture of thorax-esophagus outlet, defection of surgical technique, and so on. The fistula could be diagnosed correctly when the patient suffered high fever, dyspnea and thoracalgia after operation, with cervical anastomotic external fistula which could not been healed when the wound was opened, X-ray-showed widened mediastinum and hydropneumothorax, and drainage, esophagoraphy and CT-confirmed anastomotic fistula. All patients were cured in a short term with sufficient drainage and irrigation, enough nutrition, appropriate use of antibiotics, and pyothorax dissection and muscle flaps transplantation for bronchopleural fistula.

CONCLUSION

Most cervical anastomotic fistulas happen 1-13 days after esophagogastrostomy with critical conditions; timely diagnosis and proper treatment including operation could shorten the disease course and greatly decrease the mortality.

摘要

背景与目的

食管胃吻合术后发生颈部食管胃吻合口瘘,其内容物污染纵隔或胸腔,会形成一种特殊类型的瘘,诊断和治疗困难。处理不当则非常危险。本研究旨在分析此类瘘的发生原因、预防措施、诊断方法与标准以及恰当的治疗方法。

方法

回顾性分析我院收治的5例食管胃吻合术后颈部吻合口瘘污染纵隔或胸腔患者的临床资料,并复习相关文献。

结果

我院此类瘘的发生率为1.83%(4/219)。5例患者均在食管胃吻合术后1 - 13天发生瘘;2例出现支气管胸膜瘘。此类吻合口瘘的主要原因有吻合口压力高、吻合位置低、胸段食管出口缝合不完整、手术技术缺陷等。患者术后出现高热、呼吸困难、胸痛,颈部吻合口外瘘伤口开放不愈合,X线显示纵隔增宽、液气胸,引流、食管造影及CT证实吻合口瘘时可正确诊断。所有患者经充分引流与冲洗、充足营养支持、合理使用抗生素,以及对支气管胸膜瘘行脓胸清创和肌瓣移植后均短期内治愈。

结论

多数颈部吻合口瘘发生在食管胃吻合术后1 - 13天,病情危急;及时诊断并采取包括手术在内的恰当治疗可缩短病程,大幅降低死亡率。

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