Ono Kentaro, Morimoto Yasuhiro, Inoue Hiroko, Masuda Wataru, Tanaka Tatsurou, Inenaga Kiyotoshi
Department of Biosciences, Kyushu Dental College, 2-6-1 Manazuru, Kokurakitaku, Kitakyushu, 803-8580, Japan.
Arch Oral Biol. 2006 Apr;51(4):345-9. doi: 10.1016/j.archoralbio.2005.09.001. Epub 2005 Oct 10.
The aim of this study was to examine the relationships between gland sizes and the flow rate and composition of the unstimulated whole saliva in humans.
In 28 healthy young adults, the sizes of the three major salivary glands were estimated by use of a magnetic resonance (MR) imaging technique. Unstimulated whole saliva was collected for 5 min by the spitting method, and the flow rate and the concentrations of total protein, Na(+) and K(+) and pH were measured.
The estimated sizes of the parotid and submandibular glands showed a significant positive correlation with the flow rate and the secretion rate of total protein in the unstimulated whole saliva, but that of the sublingual glands did not. Concerning the concentrations of Na(+) and K(+) and pH, there were no correlations with the salivary gland sizes.
The results suggest that the larger the sizes of the parotid and submandibular glands, the faster the fluid flow and protein secretion rates in unstimulated whole saliva.
本研究旨在探讨人体唾液腺大小与非刺激性全唾液流速及成分之间的关系。
对28名健康青年成年人，采用磁共振成像技术估算三大唾液腺的大小。通过吐唾法收集5分钟非刺激性全唾液，测量其流速、总蛋白、钠（Na⁺）、钾（K⁺）浓度及pH值。
腮腺和下颌下腺的估算大小与非刺激性全唾液的流速及总蛋白分泌率呈显著正相关，而舌下腺则无此相关性。关于钠（Na⁺）、钾（K⁺）浓度及pH值，与唾液腺大小无相关性。
结果表明，腮腺和下颌下腺越大，非刺激性全唾液中的液体流速和蛋白质分泌率越快。
