通过铜（I）氮杂环卡宾催化的（三丁基锡基）重氮乙酸酯的非对映选择性环丙烷化反应制备锡基环丙烷。
Stannyl cyclopropanes by diastereoselective cyclopropanations with (tributylstannyl)-diazoacetate esters catalyzed by Cu(I) N-heterocyclic carbene.
作者信息
Gawley Robert E, Narayan Sanjay
机构信息
Department of Chemistry and Biochemistry, University of Arkansas, Fayetteville, AR 72701, USA.
出版信息
Chem Commun (Camb). 2005 Oct 28(40):5109-11. doi: 10.1039/b509958g. Epub 2005 Sep 19.
DOI:10.1039/b509958g
PMID:16220187
Abstract
Catalyzed cyclopropanations of alkenes with Bu3SnC(=N2)CO2R (R = Et, t-Bu) have been achieved in good yield with excellent diastereoselectivity to make stannyl cyclopropanes having two or three stereocenters, one of which is quaternary.
摘要
已实现用Bu3SnC(=N2)CO2R（R = 乙基、叔丁基）对烯烃进行催化环丙烷化反应，产率良好，非对映选择性优异，制得具有两个或三个立体中心（其中一个为季碳）的锡基环丙烷。
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