Zabel Erik W, Falken Myron C, Sonnabend Michele, Alms Maureen, Symonik Daniel
Minnesota Department of Health, Environmental Health Division, St. Paul 55164-0975, USA.
J Environ Health. 2005 Sep;68(2):9-15, 36.
The objectives of the study reported here were to determine the prevalence of elevated blood lead levels in rural Minnesota and to evaluate a lead-risk-screening questionnaire. Blood lead tests and lead risk questionnaires were obtained for a sample of 1,090 children younger than 48 months of age (72 percent of the eligible population) from three rural counties of west-central Minnesota between September 1, 2001, and August 31, 2002. It was found that overall, 2.4 percent of children in the study had blood lead levels of > or = 10 microg/dL (0.48 micromol/L) (results for capillary and venous tests combined), 0.9 percent had venous blood lead levels of > or = 10 microg/dL, and 0.5 percent of study participants had blood lead levels of > or = 20 microg/dL (0.96 micromol/L). Three risk factor questions, when taken together, predicted 90 percent of blood lead levels of > or = 10 microg/dL and all blood lead levels of > or = 20 microg/dL. The study estimated the prevalence of lead poisoning using a sample of the entire population rather than a clinic-based convenience sample. The authors conclude that targeted screening is an effective way to identify lead-poisoned children in rural areas of Minnesota.
本文所报告研究的目的是确定明尼苏达州农村地区血铅水平升高的患病率,并评估一份铅风险筛查问卷。在2001年9月1日至2002年8月31日期间,从明尼苏达州中西部三个农村县抽取了1090名48个月以下儿童(占符合条件人群的72%)作为样本,获取了他们的血铅检测结果和铅风险问卷。结果发现,总体而言,该研究中2.4%的儿童血铅水平≥10微克/分升(0.48微摩尔/升)(毛细血管血和静脉血检测结果合并),0.9%的儿童静脉血铅水平≥10微克/分升,0.5%的研究参与者血铅水平≥20微克/分升(0.96微摩尔/升)。三个风险因素问题综合起来,可预测90%血铅水平≥10微克/分升的情况以及所有血铅水平≥20微克/分升的情况。该研究使用的是全体人群的样本而非基于诊所的便利样本估计铅中毒的患病率。作者得出结论,有针对性的筛查是识别明尼苏达州农村地区铅中毒儿童的有效方法。