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北卡罗来纳州儿童城乡血铅差异

Rural-urban blood lead differences in North Carolina children.

作者信息

Norman E H, Bordley W C, Hertz-Picciotto I, Newton D A

机构信息

Preventive Services Branch, Division of Maternal and Child Health, North Carolina Department of Environment, Health, and Natural Resources, Raleigh 27611.

出版信息

Pediatrics. 1994 Jul;94(1):59-64.

PMID:8008539
Abstract

OBJECTIVE

To examine the prevalence of and risk factors for having a blood lead elevation among young children in a predominantly rural state.

METHODS

20,720 North Carolina children at least 6 months and < 6 years of age were screened between November 1, 1992 and April 30, 1993 using either capillary or venous measurements of blood lead. Children were tested through routine screening programs that target low-income families and, hence, were not randomly selected. Eighty-one percent of the children were screened through local public health departments, and 19% were tested at private clinics.

RESULTS

The estimated prevalences of having an elevated blood lead level among those tested were: 20.2% (> or = 10 micrograms/dL), 3.2% (> or = 15 micrograms/dL), and 1.1% (> or = 20 micrograms/dL). Black children were at substantially increased risk of having a blood lead > or = 15 micrograms/dL (odds ratio (OR) = 2.1, 95% confidence interval (CI) = 1.7 to 2.5). Children aged 2 years old had an elevated risk (OR = 1.4, 95% CI = 1.1 to 1.7) compared to 1-year-olds, and males were at slightly increased risk (OR = 1.2, 95% CI = 1.0 to 1.4). Living in a rural county was nearly as strong a risk factor as race (OR = 1.9, 95% CI = 1.6 to 2.4). The effect of rural residence was even greater among certain subgroups of children already at highest risk of having an elevated blood lead. The type of clinic (public vs private) where a child was screened was not associated with blood lead outcome. These same trends were seen for children with blood lead levels > or = 20 micrograms/dL.

CONCLUSIONS

Among children screened from rural communities, the prevalence of elevated blood lead is surprisingly high. Though few physicians have embraced universal lead screening, these data support the need for greater awareness of lead exposure in children living outside of inner-cities.

摘要

目的

调查一个以农村为主的州中幼儿血铅升高的患病率及其危险因素。

方法

在1992年11月1日至1993年4月30日期间,对北卡罗来纳州20720名年龄至少6个月且小于6岁的儿童进行了血铅筛查,采用毛细血管或静脉血铅测量方法。儿童通过针对低收入家庭的常规筛查项目进行检测,因此并非随机选取。81%的儿童通过当地公共卫生部门进行筛查,19%在私人诊所接受检测。

结果

在接受检测的儿童中,估计血铅水平升高的患病率分别为:20.2%(≥10微克/分升)、3.2%(≥15微克/分升)和1.1%(≥20微克/分升)。黑人儿童血铅≥15微克/分升的风险显著增加(优势比(OR)=2.1,95%置信区间(CI)=1.7至2.5)。与1岁儿童相比,2岁儿童风险升高(OR = 1.4,95% CI = 1.1至1.7),男性风险略有增加(OR = 1.2,95% CI = 1.0至1.4)。生活在农村县几乎与种族一样是一个强大的危险因素(OR = 1.9,95% CI = 1.6至2.4)。农村居住的影响在已经处于血铅升高最高风险的某些儿童亚组中甚至更大。儿童接受筛查的诊所类型(公立与私立)与血铅结果无关。血铅水平≥20微克/分升的儿童也呈现出相同趋势。

结论

在农村社区筛查的儿童中,血铅升高的患病率惊人地高。尽管很少有医生采用普遍的铅筛查,但这些数据支持有必要提高对城市以外地区儿童铅暴露的认识。

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