Hertweck Maren
Laboratory of Bioinformatics and Molecular Genetics, Institute of Biology 3, Albert-Ludwigs University of Freiburg, Schänzlestrasse 1, D-79104 Freiburg, Germany.
Sci Aging Knowledge Environ. 2005 Oct 12;2005(41):pe31. doi: 10.1126/sageke.2005.41.pe31.
The worm Caenorhabditis elegans has become a popular model organism for the study of mechanisms involved in aging. The C. elegans life span is controlled by several pathways that have been extensively characterized at the molecular level. These include pathways that regulate metabolism and development (namely, the insulin/IGF-1 pathway), nutrition, mitochondrial activity, and reproduction. Presentations at a recent C. elegans conference add to the growing body of knowledge about the genetic networks that control the complex process of aging and suggest new avenues for further investigations.
秀丽隐杆线虫已成为研究衰老相关机制的一种流行的模式生物。秀丽隐杆线虫的寿命由几条在分子水平上已得到广泛表征的通路控制。这些通路包括调节代谢和发育的通路（即胰岛素/胰岛素样生长因子-1通路）、营养、线粒体活性和生殖。在最近一次秀丽隐杆线虫会议上的报告增加了有关控制衰老这一复杂过程的遗传网络的知识体系，并为进一步研究提出了新的途径。
