Mandel Dror, Oron Tal, Mimouni Galit Sheffer, Littner Yoav, Dollberg Shaul, Mimouni Francis B
Department of Neonatology, Tel Aviv-Sourasky Medical Center, Tel Aviv, Israel.
J Perinatol. 2005 Nov;25(11):690-3. doi: 10.1038/sj.jp.7211389.
To test the hypothesis that absolute nucleated red blood cells (ANRBC) counts are higher at birth in infants who were born after prolonged rupture of membranes (PROM, >24 hours).
Retrospective study of 31 infants admitted to the neonatal intensive care unit who were born after PROM, and pair matched for gestational age and Apgar scores with 31 no PROM controls. Venous ANRBC counts were obtained within 1 hour of life.
Groups did not differ in birthweight, gestational age, Apgar scores, and platelets counts. The ANRBC counts and hematocrit were significantly higher in infants who were born after PROM than in controls.
Infants born after PROM have higher ANRBC counts at birth than control infants. We suggest that increased fetal erythropoiesis exists in infants who are delivered after PROM. If correct, our interpretation supports the theory that fetal hypoxia and/or ischemia may result from PROM.
检验以下假设：胎膜早破（PROM，>24小时）后出生的婴儿出生时绝对有核红细胞（ANRBC）计数更高。
对31例入住新生儿重症监护病房、胎膜早破后出生的婴儿进行回顾性研究，并与31例无胎膜早破的对照婴儿按胎龄和阿氏评分进行配对。在出生后1小时内获取静脉ANRBC计数。
两组在出生体重、胎龄、阿氏评分和血小板计数方面无差异。胎膜早破后出生的婴儿的ANRBC计数和血细胞比容显著高于对照组。
胎膜早破后出生的婴儿出生时的ANRBC计数高于对照婴儿。我们认为，胎膜早破后分娩的婴儿存在胎儿红细胞生成增加的情况。如果我们的解释正确，那么它支持了胎膜早破可能导致胎儿缺氧和/或缺血的理论。
