Kurokawa I, Mizutani H, Nishijima S, Kusumoto K, Tsubura A
Department of Dermatology, Mie University Graduate School of Medicine, Edobashi, Tsu, Mie, Japan.
J Int Med Res. 2005 Sep-Oct;33(5):590-3. doi: 10.1177/147323000503300515.
We describe a case of Syringocystadenoma papilliferum (SCAP) with keratinizing squamous epithelium in a 26-year-old female presenting with a dark brown to black nodule on her forehead. After surgical excision, the specimen was examined immunohistochemically using antibodies against cytokeratin (CK) 1, 8, 10, 14, 17, 18 and 19. Within the keratinizing squamous epithelium, CK1, 10, 14 and 17 were present, whereas the other CKs were absent. Based on CK expression, keratinizing squamous epithelium in SCAP seems to differentiate towards the infrainfundibulum.
我们描述了一例26岁女性的乳头状汗管囊腺瘤（SCAP），其额部有一个深棕色至黑色结节，伴有角化鳞状上皮。手术切除后，使用抗细胞角蛋白（CK）1、8、10、14、17、18和19的抗体对标本进行免疫组织化学检查。在角化鳞状上皮内，存在CK1、10、14和17，而其他CKs不存在。基于CK表达，SCAP中的角化鳞状上皮似乎向漏斗下部分化。
