Geurts A C, Mulder T W, Nienhuis B, Mars P, Rijken R A
Department of Research and Development, Nijmegen, The Netherlands.
Arch Phys Med Rehabil. 1992 Jun;73(6):569-72.
The postural organization in patients with hereditary motor and sensory neuropathy (HMSN) type I or II was studied clinically by means of a force platform. Balance was registered in 14 barefooted HMSN patients and healthy matched control subjects during quiet stance. The effect of visual deprivation was tested to determine the degree of visual dependency. The effect of the simultaneous performance of a concurrent attention-demanding task (Stroop task) was tested to estimate the level of balance automaticity. In comparison with control subjects, the HMSN patients showed a basically decreased efficiency of postural control (p less than .01) as well as an increased visual control of posture (p less than .05) in both directions of sway. No loss of balance automaticity was found, which suggested an on-line central adaptation to the slowly developing peripheral impairments. The results provide a starting point for understanding the balance problems and gross motor disabilities in HMSN patients.
采用测力平台对Ⅰ型或Ⅱ型遗传性运动感觉神经病（HMSN）患者的姿势组织进行了临床研究。在安静站立时，对14名赤足的HMSN患者和健康对照受试者的平衡情况进行了记录。通过测试视觉剥夺的影响来确定视觉依赖程度。通过测试同时执行一项需要注意力的并发任务（斯特鲁普任务）的影响来评估平衡自动性水平。与对照受试者相比，HMSN患者在两个摆动方向上均表现出姿势控制效率基本下降（p<0.01）以及姿势的视觉控制增加（p<0.05）。未发现平衡自动性丧失，这表明对缓慢发展的周围神经损伤存在在线中枢适应性。这些结果为理解HMSN患者的平衡问题和严重运动障碍提供了一个起点。
