Wachter Rebekka M
Department of Chemistry and Biochemistry, Arizona State University, Tempe, AZ 85287, USA.
Photochem Photobiol. 2006 Mar-Apr;82(2):339-44. doi: 10.1562/2005-10-02-IR-708.
In this issue, we offer a symposium-in-print that is focused on several new advancements in fundamental research related to the family of GFP (green fluorescent protein)-like proteins. A few applied aspects are also included to illustrate the impact this amazing set of colored proteins has made on our understanding of cell biology at the molecular level. The six articles presented here cut across several disciplines ranging from biological function to protein structure to photophysical aspects. These highly original pieces of work include both experimental and computational approaches, and will provide the reader with significant insight into current, state-of-the-art research activities in this very dynamic and fast-paced field. In the first part of this perspective, I will give a brief overview of the history and salient features of GFPs, cite some examples that illustrate their impact on biotechnology, and provide a brief review of the structural and chemical features that lend these proteins their fascinating appearance. In the second part, I will introduce each of the peer-reviewed contributions of the participating authors.
在本期中，我们提供了一个印刷版专题研讨会，重点关注与绿色荧光蛋白（GFP）类蛋白家族相关的基础研究中的几项新进展。还包括了一些应用方面的内容，以说明这一系列令人惊叹的彩色蛋白对我们在分子水平上理解细胞生物学所产生的影响。这里呈现的六篇文章涵盖了从生物学功能到蛋白质结构再到光物理方面的多个学科。这些极具原创性的作品包括实验方法和计算方法，将为读者提供对这个非常活跃和快节奏领域当前最前沿研究活动的重要见解。在这个视角的第一部分，我将简要概述绿色荧光蛋白的历史和显著特征，引用一些说明它们对生物技术影响的例子，并简要回顾赋予这些蛋白迷人外观的结构和化学特征。在第二部分，我将介绍参与作者的每一篇经过同行评审的稿件。
