Transcriptional downregulation of the lactase (LCT) gene during childhood.
作者信息
Rasinperä H, Kuokkanen M, Kolho K-L, Lindahl H, Enattah N S, Savilahti E, Orpana A, Järvelä I
出版信息
Gut. 2005 Nov;54(11):1660-1. doi: 10.1136/gut.2005.077404.
Abstract
摘要
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Gut. 2005 Nov;54(11):1660-1. doi: 10.1136/gut.2005.077404.
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本文引用的文献
1
Adult-type hypolactasia and regulation of lactase expression.成人型乳糖酶缺乏与乳糖酶表达的调控
Biochim Biophys Acta. 2005 May 25;1723(1-3):19-32. doi: 10.1016/j.bbagen.2005.02.003. Epub 2005 Feb 25.
2
A genetic test which can be used to diagnose adult-type hypolactasia in children.一种可用于诊断儿童成人型低乳糖酶症的基因检测。
Gut. 2004 Nov;53(11):1571-6. doi: 10.1136/gut.2004.040048.
3
An upstream polymorphism associated with lactase persistence has increased enhancer activity.与乳糖酶持续性相关的一个上游多态性增加了增强子活性。
Gastroenterology. 2003 Dec;125(6):1686-94. doi: 10.1053/j.gastro.2003.09.031.
4
Lactase persistence DNA variant enhances lactase promoter activity in vitro: functional role as a cis regulatory element.乳糖酶持续性DNA变异体在体外增强乳糖酶启动子活性：作为顺式调控元件的功能作用
Hum Mol Genet. 2003 Sep 15;12(18):2333-40. doi: 10.1093/hmg/ddg244. Epub 2003 Jul 22.
5
Transcriptional regulation of the lactase-phlorizin hydrolase gene by polymorphisms associated with adult-type hypolactasia.与成人型乳糖酶缺乏相关的多态性对乳糖酶-根皮苷水解酶基因的转录调控
Gut. 2003 May;52(5):647-52. doi: 10.1136/gut.52.5.647.
6
Identification of a variant associated with adult-type hypolactasia.一种与成人型低乳糖酶症相关变异体的鉴定。
Nat Genet. 2002 Feb;30(2):233-7. doi: 10.1038/ng826. Epub 2002 Jan 14.
7
The genetically programmed down-regulation of lactase in children.儿童乳糖酶的基因程序性下调。
Gastroenterology. 1998 Jun;114(6):1230-6. doi: 10.1016/s0016-5085(98)70429-9.
8
Genetics and epidemiology of adult-type hypolactasia.成人型乳糖不耐受的遗传学与流行病学
Scand J Gastroenterol Suppl. 1994;202:7-20. doi: 10.3109/00365529409091740.
9
Congenital lactase deficiency. A clinical study on 16 patients.先天性乳糖酶缺乏症。16例患者的临床研究。
Arch Dis Child. 1983 Apr;58(4):246-52. doi: 10.1136/adc.58.4.246.
10
Assay of intestinal disaccharidases.肠道双糖酶测定
Scand J Clin Lab Invest. 1984 Apr;44(2):169-72. doi: 10.3109/00365518409161400.
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