Gernez Y, Barlési F, Doddoli C, Chetaille B, Forel J M, Astoul P, Papazian L
Service de Réanimation Médicale, Hôpital Sainte-Marguerite, Faculté de Médecine, Université de la Méditerranée, Assistance Publique Hôpitaux de Marseille, Marseille, France.
Rev Mal Respir. 2005 Jun;22(3):477-80. doi: 10.1016/s0761-8425(05)85576-7.
Barium sulfate (BS) is chosen to explore swallowing disorders because of its reduced osmolality allowing no adverse reaction if aspirated in the bronchial tree.
A 66-years old man treated for an advanced stage mesothelioma experienced a BS aspiration during an esophagography. He developed 3 days after an acute respiratory distress syndrome (ARDS) and deceased. The post-mortem examination revealed a diffuse alveolar damage (DAD).
Whereas BS aspiration is generally well tolerated, serious adverse event as a DAD would exceptionally occurs. Thus, a close watch over respiratory symptoms has to be kept after BS administration, especially in debilitated and elderly patients.
硫酸钡（BS）因其低渗性被选用于吞咽障碍的检查，若被误吸入支气管树不会产生不良反应。
一名66岁患有晚期间皮瘤的男性在食管造影检查期间发生了硫酸钡误吸。3天后他出现急性呼吸窘迫综合征（ARDS）并死亡。尸检显示为弥漫性肺泡损伤（DAD）。
虽然硫酸钡误吸通常耐受性良好，但像弥漫性肺泡损伤这样的严重不良事件仍可能罕见发生。因此，在给予硫酸钡后必须密切观察呼吸症状，尤其是在体弱和老年患者中。
