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Desmin cytoskeleton in healthy and failing heart.

作者信息

Capetanaki Y

机构信息

Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas 77030, USA.

出版信息

Heart Fail Rev. 2000 Oct;5(3):203-20. doi: 10.1023/A:1009853302447.

DOI:10.1023/A:1009853302447
PMID:16228905
Abstract
摘要

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Desmin cytoskeleton in healthy and failing heart.健康及衰竭心脏中的结蛋白细胞骨架
Heart Fail Rev. 2000 Oct;5(3):203-20. doi: 10.1023/A:1009853302447.
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The toxic effect of R350P mutant desmin in striated muscle of man and mouse.R350P 突变型结蛋白在人和小鼠横纹肌中的毒性作用。
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Desmin-free cardiomyocytes and myocardial dysfunction in end stage heart failure.终末期心力衰竭中无结蛋白心肌细胞与心肌功能障碍
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Desmin cytoskeleton: a potential regulator of muscle mitochondrial behavior and function.结蛋白细胞骨架:肌肉线粒体行为和功能的潜在调节因子。
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Changes of desmin expression pattern in the myocardium of patients with alcoholic dilated cardiomyopathy.酒精性扩张型心肌病患者心肌中结蛋白表达模式的变化
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Genetic modification of the heart: chaperones and the cytoskeleton.心脏的基因改造:伴侣蛋白与细胞骨架
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Cardiomyocyte-specific disruption of Cathepsin K protects against doxorubicin-induced cardiotoxicity.心肌细胞特异性组织蛋白酶 K 缺失可预防阿霉素诱导的心脏毒性。
Cell Death Dis. 2018 Jun 7;9(6):692. doi: 10.1038/s41419-018-0727-2.
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The role of protein kinase C-mediated phosphorylation of sarcomeric proteins in the heart-detrimental or beneficial?蛋白激酶C介导的肌节蛋白磷酸化在心脏中起有害还是有益作用?
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本文引用的文献

1
The contractile apparatus of smooth muscle.平滑肌的收缩装置。
Int Rev Cytol. 1980;64:241-306. doi: 10.1016/s0074-7696(08)60239-9.
2
Desmin integrates the three-dimensional mechanical properties of muscles.结蛋白整合肌肉的三维力学特性。
Am J Physiol Cell Physiol. 2001 Jan;280(1):C46-52. doi: 10.1152/ajpcell.2001.280.1.C46.
3
Desmin knockout muscles generate lower stress and are less vulnerable to injury compared with wild-type muscles.与野生型肌肉相比,结蛋白基因敲除的肌肉产生的应力较低,且不易受伤。
肌联蛋白:一种多功能的结蛋白相关蛋白。
Histochem Cell Biol. 2013 Jul;140(1):55-63. doi: 10.1007/s00418-013-1103-z. Epub 2013 Jun 9.
4
Effect of ouabain on myocardial ultrastructure and cytoskeleton during the development of ventricular hypertrophy.哇巴因对心室肥厚发展过程中心肌超微结构和细胞骨架的影响。
Heart Vessels. 2013 Jan;28(1):101-13. doi: 10.1007/s00380-011-0219-0. Epub 2012 Jan 13.
5
Right ventricular remodeling in restrictive ventricular septal defect.右室重构在限制性室间隔缺损中的作用。
J Mol Cell Cardiol. 2010 Oct;49(4):699-706. doi: 10.1016/j.yjmcc.2010.07.005. Epub 2010 Jul 15.
6
Cell-cell connection to cardiac disease.细胞间连接与心脏疾病。
Trends Cardiovasc Med. 2009 Aug;19(6):182-90. doi: 10.1016/j.tcm.2009.12.001.
7
Proteomic profiling of endothelin-1-stimulated hypertrophic cardiomyocytes reveals the increase of four different desmin species and alpha-B-crystallin.内皮素-1刺激的肥厚型心肌细胞的蛋白质组分析显示四种不同的结蛋白亚型和α-B-晶状体蛋白增加。
Biochim Biophys Acta. 2008 Jul-Aug;1784(7-8):1068-76. doi: 10.1016/j.bbapap.2008.04.003. Epub 2008 Apr 18.
8
Desmin stimulates differentiation of cardiomyocytes and up-regulation of brachyury and nkx2.5.结蛋白刺激心肌细胞分化以及短尾相关蛋白和NKX2.5的上调。
Differentiation. 2007 Sep;75(7):605-15. doi: 10.1111/j.1432-0436.2007.00162.x. Epub 2007 Mar 23.
9
The cytoskeleton and related proteins in the human failing heart.人类衰竭心脏中的细胞骨架及相关蛋白
Heart Fail Rev. 2000 Oct;5(3):271-80. doi: 10.1023/A:1009813621103.
10
Extensive induction of important mediators of fibrosis and dystrophic calcification in desmin-deficient cardiomyopathy.在结蛋白缺乏性心肌病中,纤维化和营养不良性钙化的重要介质被广泛诱导。
Am J Pathol. 2002 Mar;160(3):943-52. doi: 10.1016/S0002-9440(10)64916-4.
Am J Physiol Cell Physiol. 2000 Oct;279(4):C1116-22. doi: 10.1152/ajpcell.2000.279.4.C1116.
4
Desmin cytoskeleton linked to muscle mitochondrial distribution and respiratory function.结蛋白细胞骨架与肌肉线粒体分布及呼吸功能相关。
J Cell Biol. 2000 Sep 18;150(6):1283-98. doi: 10.1083/jcb.150.6.1283.
5
Desmin myopathy, a skeletal myopathy with cardiomyopathy caused by mutations in the desmin gene.结蛋白肌病,一种由结蛋白基因突变引起的伴有心肌病的骨骼肌病。
N Engl J Med. 2000 Mar 16;342(11):770-80. doi: 10.1056/NEJM200003163421104.
6
Activity-dependent interaction of the intracellular domain of rat trkA with intermediate filament proteins, the beta-6 proteasomal subunit, Ras-GRF1, and the p162 subunit of eIF3.大鼠trkA细胞内结构域与中间丝蛋白、β-6蛋白酶体亚基、Ras-GRF1和eIF3的p162亚基的活性依赖性相互作用。
J Mol Neurosci. 1999 Aug-Oct;13(1-2):141-58. doi: 10.1385/JMN:13:1-2:141.
7
The absence of desmin leads to cardiomyocyte hypertrophy and cardiac dilation with compromised systolic function.结蛋白的缺失会导致心肌细胞肥大、心脏扩张,收缩功能受损。
J Mol Cell Cardiol. 1999 Nov;31(11):2063-76. doi: 10.1006/jmcc.1999.1037.
8
Balance between activities of Rho kinase and type 1 protein phosphatase modulates turnover of phosphorylation and dynamics of desmin/vimentin filaments.Rho激酶与1型蛋白磷酸酶活性之间的平衡调节磷酸化的周转以及结蛋白/波形蛋白丝的动力学。
J Biol Chem. 1999 Dec 3;274(49):34932-9. doi: 10.1074/jbc.274.49.34932.
9
The cardiomyopathy and lens cataract mutation in alphaB-crystallin alters its protein structure, chaperone activity, and interaction with intermediate filaments in vitro.αB-晶状体蛋白中的心肌病和晶状体白内障突变在体外会改变其蛋白质结构、伴侣活性以及与中间丝的相互作用。
J Biol Chem. 1999 Nov 19;274(47):33235-43. doi: 10.1074/jbc.274.47.33235.
10
A missense mutation in the desmin rod domain is associated with autosomal dominant distal myopathy, and exerts a dominant negative effect on filament formation.结蛋白杆状结构域中的错义突变与常染色体显性遗传性远端肌病相关,并对细丝形成产生显性负效应。
Hum Mol Genet. 1999 Nov;8(12):2191-8. doi: 10.1093/hmg/8.12.2191.