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动脉栓塞及预防性置管治疗严重产科出血*

Arterial embolization and prophylactic catheterization for the treatment for severe obstetric hemorrhage*.

作者信息

Ojala Kati, Perälä Jukka, Kariniemi Juho, Ranta Pirjo, Raudaskoski Tytti, Tekay Aydin

机构信息

Department of Obstetrics and Gynecology, University of Oulu, Finland.

出版信息

Acta Obstet Gynecol Scand. 2005 Nov;84(11):1075-80. doi: 10.1111/j.0001-6349.2005.00727.x.

Abstract

BACKGROUND

To evaluate indications, efficacy, and complications associated with arterial embolization and prophylactic balloon catheterization in the management of obstetric hemorrhage at a university hospital.

METHODS

Twenty-two women underwent arterial embolization between February 2001 and November 2003 for the treatment for primary postpartum hemorrhage resulting from abnormal placentation (n=11), uterine atony (n=7), paravaginal laceration (n=3), and disseminated intravascular coagulopathy (n=1). Blood loss was between 3.2 and 15 l. In seven patients, abnormal placentation was diagnosed prenatally and in these patients balloon catheterization was performed prophylactically before elective cesarean section.

RESULTS

Of the seven patients, who underwent prophylactic catheterization, embolization was successful in five resulting in adequate hemostasis. Hysterectomy was performed in three, in two patients for uncontrolled hemorrhage and in one patient for placental invasion to bladder. There were no complications associated with prophylactic catheterization and embolization. The other 15 patients were treated in an emergency setting. In eight patients, embolization was performed as a primary surgery, and it was successful in six. In the other seven patients, hysterectomy was performed as an emergency surgery, but bleeding continued. Of these, in six patients, hemostasis was achieved with embolization. Complications associated with emergency embolization were observed in three patients. These were thrombosis of left popliteal artery, vaginal necrosis, and paresthesia of the right leg.

CONCLUSIONS

Arterial embolization is of significant value in treating obstetric hemorrhage. Prophylactic insertion of balloon catheters before cesarean section seems to be a safe and effective method in controlling anticipated bleeding. In patients with persistent bleeding following cesarean section and hysterectomy, embolization could be a primary procedure before re-surgery.

摘要

背景

评估在一所大学医院中,动脉栓塞术和预防性球囊导管插入术在处理产科出血时的适应证、疗效及并发症。

方法

2001年2月至2003年11月期间,22名女性因胎盘异常(n = 11)、子宫收缩乏力(n = 7)、阴道旁裂伤(n = 3)和弥散性血管内凝血(n = 1)导致的原发性产后出血接受了动脉栓塞术治疗。失血量在3.2升至15升之间。7名患者产前诊断为胎盘异常,这些患者在择期剖宫产术前进行了预防性球囊导管插入术。

结果

在接受预防性导管插入术的7名患者中,5名栓塞成功,实现了充分止血。三名患者接受了子宫切除术,两名因出血无法控制,一名因胎盘侵入膀胱。预防性导管插入术和栓塞术均未出现并发症。其他15名患者在急诊情况下接受治疗。8名患者将栓塞术作为主要手术,6名成功。其他7名患者接受了急诊子宫切除术,但出血仍持续。其中,6名患者通过栓塞术实现了止血。3名患者出现了与急诊栓塞术相关的并发症。分别为左腘动脉血栓形成、阴道坏死和右腿感觉异常。

结论

动脉栓塞术在治疗产科出血方面具有重要价值。剖宫产术前预防性插入球囊导管似乎是控制预期出血的一种安全有效的方法。对于剖宫产和子宫切除术后持续出血的患者,栓塞术可作为再次手术前的主要治疗手段。

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