Bennett A M D, Clark A B, Bath A P, Montgomery P Q
Department of ENT, Norfolk and Norwich University Hospital, Norwich, UK.
Clin Otolaryngol. 2005 Oct;30(5):418-23. doi: 10.1111/j.1365-2273.2005.01060.x.
To perform a meta-analysis of studies of the timing of primary tonsillectomy haemorrhage. In particular to compare the difference in risk between 0-8 and 8-24 h; that is whether overnight inpatient tonsillectomy is required.
Medline search of all tonsillectomy studies to perform a meta-analysis of the timing of primary haemorrhages.
Literature-based study.
All adult and paediatric tonsillectomy studies giving the absolute number and timing of all primary haemorrhages.
The overall incidence of haemorrhage occurring between 0-8 and 8-24 h. The overall incidence of haemorrhage for each of the first 24 h after operation. Compare risk of a bleed occurring 0-8, 8-24 and >24 h where data were available.
From a 1.4% overall risk of a primary haemorrhage only one in 14 occur after 8 h, i.e. 0.1% (95% CI=0.08-0.16%). A total of 833 patients would require to be kept overnight in order to identify one case of bleeding after 8 h.
Little benefit was conferred from overnight admission from the point of view of monitoring for primary haemorrhage. A case can be made for either day-case tonsillectomy (hospital stay over the period in which 93% of primary haemorrhages would occur) or the 'belt-and-braces' approach of a 1-week stay (during which all haemorrhages would occur) but current 24-h admission appears illogical.
对原发性扁桃体切除术后出血时间的研究进行荟萃分析。特别比较0 - 8小时和8 - 24小时之间的风险差异;即是否需要过夜住院扁桃体切除术。
通过Medline搜索所有扁桃体切除术研究,以对原发性出血时间进行荟萃分析。
基于文献的研究。
所有给出原发性出血的绝对数量和时间的成人及儿童扁桃体切除术研究。
0 - 8小时和8 - 24小时之间出血的总体发生率。术后头24小时内每小时出血的总体发生率。在有数据的情况下,比较0 - 8小时、8 - 24小时和>24小时出血的风险。
原发性出血的总体风险为1.4%,8小时后发生出血的仅为十四分之一,即0.1%(95%可信区间=0.08 - 0.16%)。总共需要833名患者过夜留院观察,才能识别出1例8小时后出血的病例。
从监测原发性出血的角度来看,过夜住院获益不大。对于日间扁桃体切除术(93%的原发性出血会在此期间发生)或为期1周住院观察(所有出血均会在此期间发生)的“双重保险”方法都有理由,但目前24小时住院似乎不合逻辑。