基因表达谱的时间进程数据分析揭示了purR调控子与大肠杆菌对有机溶剂耐受性的关系。
Time-course data analysis of gene expression profiles reveals purR regulon concerns in organic solvent tolerance in Escherichia coli.
作者信息
Shimizu Kazunori, Hayashi Shuhei, Doukyu Noriyuki, Kobayashi Takeshi, Honda Hiroyuki
机构信息
Department of Biotechnology, School of Engineering, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8603, Japan.
出版信息
J Biosci Bioeng. 2005 Jan;99(1):72-4. doi: 10.1263/jbb.99.72.
PMID:16233757
Abstract
A time-course gene-expression profile was generated for Escherichia coli TK31 when it was exposed to an organic solvent mixture, and classified by fuzzy adaptive resonance theory (Fuzzy ART). It was found that the purR regulon plays an important role in the organic solvent tolerance (OST) of E. coli.
摘要
当大肠杆菌TK31暴露于有机溶剂混合物时，生成了其随时间变化的基因表达谱，并通过模糊自适应共振理论（Fuzzy ART）进行分类。结果发现，purR调控子在大肠杆菌的有机溶剂耐受性（OST）中起重要作用。
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