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住院糖尿病患者特定病因死亡率的种族差异:新西兰的一项关联研究。

Ethnic differences in cause specific mortality among hospitalised patients with diabetes: a linkage study in New Zealand.

作者信息

Jeffreys Mona, Wright Craig, 't Mannetje Andrea, Huang Ken, Pearce Neil

机构信息

Centre for Public Health Research, Massey University, Private Bag 756, Wellington, New Zealand.

出版信息

J Epidemiol Community Health. 2005 Nov;59(11):961-6. doi: 10.1136/jech.2005.037515.

Abstract

STUDY OBJECTIVE

To describe patterns of excess mortality among patients with diabetes in three ethnic groups.

DESIGN

A linkage study of national hospital discharge records to death records.

SETTING

New Zealand.

PARTICIPANTS

The study included 74 847 patients (11,268 Māori, 5730 Pacific, and 57,849 non-Māori/non-Pacific) aged over 25 years with a hospital discharge diagnosis of diabetes between 1988 and 2001. By the end of 2001, 29,295 (39%) of the cohort had died. Based on the underlying cause of death, standardised mortality ratios (SMRs) (95% confidence intervals) were calculated for each ethnic group and sex.

MAIN RESULTS

Comparing the mortality patterns of patients with diabetes to the general population of the same ethnic group, adjusting for age and calendar period, all cause SMRs were higher for Māori women and men: 3.80 (95% CI: 3.64 to 3.97) and 3.44 (95%CI: 3.30 to 3.58) than for Pacific (men: 2.41 (95%CI: 2.21 to 2.61); women: 2.23 (95%CI: 2.06 to 2.41)) and non-Māori/non-Pacific (men: 2.98 (95%CI: 2.93 to 3.04); women: 2.99 (95%CI: 2.93 to 3.04)) people. SMRs were significantly raised for several causes of death, including cardiovascular disease and many site specific cancers.

CONCLUSIONS

The pattern of excess mortality among Māori with diabetes may relate to severity of disease. This needs further investigation, as the excess mortality may be amenable to intervention.

摘要

研究目的

描述三个种族糖尿病患者的超额死亡率模式。

设计

一项将国家医院出院记录与死亡记录相联系的研究。

地点

新西兰。

参与者

该研究纳入了74847名25岁以上的患者(11268名毛利人、5730名太平洋岛民以及57849名非毛利/非太平洋岛民),他们在1988年至2001年间因糖尿病出院诊断而住院。到2001年底,该队列中有29295人(39%)死亡。根据死亡的根本原因,计算了每个种族和性别的标准化死亡率(SMR)(95%置信区间)。

主要结果

将糖尿病患者的死亡率模式与同一种族的普通人群进行比较,在调整年龄和日历期后,毛利族女性和男性的全因SMR均高于太平洋岛民(男性:2.41(95%置信区间:2.21至2.61);女性:2.23(95%置信区间:2.06至2.41))和非毛利/非太平洋岛民(男性:2.98(95%置信区间:2.93至3.04);女性:2.99(95%置信区间:2.93至3.04)),分别为3.80(95%置信区间:3.64至3.97)和3.44(95%置信区间:3.30至3.58)。几种死因的SMR显著升高,包括心血管疾病和许多特定部位的癌症。

结论

毛利族糖尿病患者的超额死亡率模式可能与疾病严重程度有关。这需要进一步研究,因为超额死亡率可能适合进行干预。

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