Yorke J, Fleming S, Shuldham C
Royal Brompton Hospital, Sydney Street, London, UK.
Cochrane Database Syst Rev. 2005 Oct 19;2005(4):CD003272. doi: 10.1002/14651858.CD003272.pub2.
Asthma is a chronic disease of inflammation and smooth muscle dysfunction, including bronchoconstriction. These symptoms are usually associated with widespread but variable airflow obstruction that is often reversible either spontaneously or with treatment. Psychological factors may influence the symptoms and management of asthma in children in many ways, for example, evidence suggests that emotional stress can either precipitate or exacerbate both acute and chronic asthma.
To assess the efficacy of psychological interventions in improving health and behavioural outcomes for children with asthma.
The Cochrane Airways Group Specialised Register and PsycINFO were searched with pre-defined terms up until March 2005.
Randomised controlled trials published in any language assessing the effects of a psychological intervention compared with a control intervention in children and adolescents with asthma were included in the review. Cross-over trials were considered inappropriate for studies using psychological interventions and were therefore excluded from this systematic review.
Two reviewers assessed the relevance of abstracts identified by electronic searching and retrieved agreed studies for further scrutiny. The studies that met the inclusion criteria were assembled and data extracted.
Twelve studies (588 children) were included in the review. Study quality was poor and sample sizes were frequently small. A meta-analysis was possible on two studies only examining the effects of relaxation therapy on PEFR which favoured the treatment group (32 L/min, 95% CI 13 to 50 L/min). No other meta-analysis could be performed due to the diversity of interventions and the outcomes assessed. In addition, many studies reported insufficient data.
AUTHORS' CONCLUSIONS: This review was unable to draw firm conclusions for the role of psychological interventions for children with asthma. This review demonstrates the absence of an adequate evidence base and highlights the need for well-conducted and reported randomised trials in this area.
哮喘是一种炎症和平滑肌功能障碍的慢性疾病,包括支气管收缩。这些症状通常与广泛但可变的气流阻塞有关,这种阻塞往往可自发或通过治疗逆转。心理因素可能在许多方面影响儿童哮喘的症状和管理,例如,有证据表明情绪压力可引发或加重急性和慢性哮喘。
评估心理干预对改善哮喘儿童健康和行为结局的疗效。
截至2005年3月,使用预定义术语检索Cochrane气道组专业注册库和PsycINFO。
纳入本综述的研究为以任何语言发表的随机对照试验,评估心理干预与对照干预相比对哮喘儿童和青少年的影响。交叉试验被认为不适用于使用心理干预的研究,因此被排除在本系统评价之外。
两名评价员评估通过电子检索识别的摘要的相关性,并检索达成一致的研究进行进一步审查。收集符合纳入标准的研究并提取数据。
本综述纳入了12项研究(588名儿童)。研究质量较差,样本量通常较小。仅对两项研究进行了荟萃分析,这两项研究考察了放松疗法对呼气峰流速(PEFR)的影响,结果支持治疗组(32升/分钟,95%可信区间13至50升/分钟)。由于干预措施和评估结局的多样性,无法进行其他荟萃分析。此外,许多研究报告的数据不足。
本综述无法就心理干预对哮喘儿童的作用得出确切结论。本综述表明缺乏充分的证据基础,并强调了在该领域开展良好且报告规范的随机试验的必要性。