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超重引力影响后人体中的脂质过氧化与抗氧化防御系统

Lipid peroxidation and the system of antioxidant defence in humans after hypergravitational influence.

作者信息

Markin Andrei, Juravlyova Olga, Lukianuk Vasily

机构信息

State Scientific Center of Russian Federation Institute for Biomedical Problems Russian Academy of Sciences, Moscow, Russia.

出版信息

J Gravit Physiol. 2004 Jul;11(2):P69-70.

Abstract

Hypergravitational influence (HI) +Gz (head-pelvis) within ranges of up to 3, up to 5, and up to 7 g with an acceleration speed of 0.03 g/s was applied to a group of men of an age of 25 to 45 y.o. In their blood serum the parameters of lipid peroxidation (LP) and the system of antioxidant defence (AOD) had been studied. HI results in LP intensity changing in a human body. HI increasing caused an increase in a number of AOD components involved in the free radical processes (FRP) compensation and functioning in a water phase. The characteristics of AOD lipid-phase link does not change. The mechanisms of compensating and monitoring of FRP intensity at HI required further studies.

摘要

在加速度为0.03 g/s的情况下,对一组年龄在25至45岁的男性施加高达3 g、5 g和7 g范围内的超重影响(HI)+Gz(头部-骨盆方向)。研究了他们血清中脂质过氧化(LP)参数和抗氧化防御系统(AOD)。超重影响导致人体中LP强度发生变化。超重影响增加导致参与自由基过程(FRP)补偿并在水相中发挥作用的AOD成分数量增加。AOD脂质相联系的特征没有改变。超重影响下FRP强度的补偿和监测机制需要进一步研究。

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