2-芳基-3-硅基-1,3-丁二烯的制备与反应

Preparation and reaction of 2-aryl-3-silyl-1,3-butadiene.

作者信息

Ikeda Zenichi, Oshima Koichiro, Matsubara Seijiro

机构信息

Department of Material Chemistry, Graduate School of Engineering, Kyoto University, Kyoutodaigaku-katsura, Nishikyo, Japan.

出版信息

Org Lett. 2005 Oct 27;7(22):4859-61. doi: 10.1021/ol051557s.

DOI:10.1021/ol051557s

PMID:16235907

Abstract

[reaction: see text] A conjugated pi-electron compound, 2-aryl-3-silyl-1,3-butadiene, was easily prepared from 1-benzyloxy-3-silyl-2-propyne, bis(iodozincio)methane, and an aryl halide in the presence of nickel catalyst. A subsequent cross-coupling reaction of the product with another aryl halide gave an unsymmetrical 2,3-diaryl-1,3-butadiene efficiently.

摘要

[反应：见正文] 一种共轭π电子化合物，2-芳基-3-硅基-1,3-丁二烯，可在镍催化剂存在下，由1-苄氧基-3-硅基-2-丙炔、双（碘锌基）甲烷和芳基卤化物轻松制备。所得产物与另一种芳基卤化物随后的交叉偶联反应高效地得到了不对称的2,3-二芳基-1,3-丁二烯。