Haddad Peiman, Kalaghchi Bita, Amouzegar-Hashemi Farnaz
Radiation Oncology Department, Cancer Institute, Tehran University of Medical Sciences, Tehran, Iran.
Radiother Oncol. 2005 Dec;77(3):324-6. doi: 10.1016/j.radonc.2005.09.014. Epub 2005 Oct 17.
We treated 34 radiation-induced superficial fibrotic lesions with pentoxifylline and vitamin E for 3 months. Mean surface area of the lesions decreased from 112 to 65 cm(2) after treatment (P<0.001). A subgroup of 21 fibrotic lesions received the medications for 6 months, in which surface area decreased from 80 to 27 cm(2) (P<0.001). Pentoxifylline-vitamin E combination improved radiation-induced fibrosis.
我们用己酮可可碱和维生素E治疗34例放射性浅表纤维化病变，为期3个月。治疗后病变的平均表面积从112平方厘米降至65平方厘米（P<0.001）。21例纤维化病变的亚组接受药物治疗6个月，其表面积从80平方厘米降至27平方厘米（P<0.001）。己酮可可碱 - 维生素E联合用药改善了放射性纤维化。
