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[鼻咽癌治疗后发生的丹毒]

[Erysipela after treatment of nasopharyngeal carcinoma].

作者信息

Daoud J, Elloumi F, Maaloul I, Toumi N, Ghorbel A, Ben Jemaa M, Frikha M, Drira M M

机构信息

Service de radiothérapie carcinologique, CHU Habib-Bourguiba, Sfax, Tunisie.

出版信息

Cancer Radiother. 2005 Dec;9(8):587-9. doi: 10.1016/j.canrad.2005.09.014. Epub 2005 Oct 19.

Abstract

PURPOSE

The aim of this work is to study the epidemiological, clinical and evolutive characteristics of the erysipela in patients treated for nasopharyngeal carcinoma (NPC).

PATIENTS AND METHODS

Between January 1993 and June 2003, 212 patients were treated for NPC in the radiotherapy department of Sfax hospital. Twenty-two patients among them have presented an erysipela. A neoadjuvant chemotherapy was used for 16 patients with N2-N3 disease. Locoregional radiotherapy was delivered for all of patients.

RESULTS

The mean age was 35 years (range: 10 and 69), sex-ratio was 1.2. The median delay between the appearance of erysipela and the end of the treatment was 16 months. The main localisation was the face. The main clinical manifestations were fever in 86% of cases and erythema in 77% of cases. Immediate evolution was favorable in all cases after antibiotherapy. Recurrences were observed in 45% in cases.

CONCLUSION

Erysipela is a common skin infection readly found in patients with venous insufficiency. In our study we found a significant correlation between the frequency of erysipela and dystrophic complications. The incidence of erysipela in the face and cervical region after radiotherapy is unknown.

摘要

目的

本研究旨在探讨鼻咽癌(NPC)患者中丹毒的流行病学、临床及演变特征。

患者与方法

1993年1月至2003年6月期间,斯法克斯医院放疗科对212例患者进行了鼻咽癌治疗。其中22例患者出现了丹毒。16例N2 - N3期疾病患者采用了新辅助化疗。所有患者均接受了局部区域放疗。

结果

平均年龄为35岁(范围:10至69岁),性别比为1.2。丹毒出现至治疗结束的中位间隔时间为16个月。主要发病部位为面部。主要临床表现为86%的病例有发热,77%的病例有红斑。所有病例经抗生素治疗后即刻病情好转。45%的病例出现复发。

结论

丹毒是静脉功能不全患者中常见的皮肤感染。在我们的研究中,发现丹毒发生频率与营养不良并发症之间存在显著相关性。放疗后面部和颈部丹毒的发病率尚不清楚。

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