对席尔瓦等人的回应：基于聚合酶链反应的方法在流行病学研究中筛查利什曼原虫的实用性。

Response to Silva et al.: Usefulness of PCR-based methods for screening Leishmania in epidemiological studies.

作者信息

Oliveira Fernanda S, Brazil Reginaldo P, Pacheco Raquel S

机构信息

Department of Biochemistry and Molecular Biology, Instituto Oswaldo Cruz, Fiocruz, 21040-900 Rio de Janeiro, Brazil.

出版信息

Trends Parasitol. 2005 Dec;21(12):552-3. doi: 10.1016/j.pt.2005.09.009. Epub 2005 Oct 17.

DOI:10.1016/j.pt.2005.09.009

PMID:16236549

Abstract

The detection of Leishmania in naturally infected rodents in endemic areas is of fundamental importance for defining these rodents as possible reservoir hosts of infection. The use of polymerase chain reaction in conjunction with molecular hybridization has provided important results that could lead to a better understanding of the natural history of leishmaniasis.

摘要

在流行地区自然感染利什曼原虫的啮齿动物中进行检测，对于确定这些啮齿动物是否可能作为感染的储存宿主至关重要。聚合酶链反应与分子杂交相结合的方法已取得重要成果，这可能有助于更好地了解利什曼病的自然史。