Buchner H, Höpfner U, Biniek R, Ferbert A
Department of Neurology, University Hospital RWTH, Aachen, FRG.
Electromyogr Clin Neurophysiol. 1992 Jun;32(6):311-6.
Subcortical and cortical somatosensory evoked potentials (SEP) to median nerve stimulation were recorded before, during and after high frequency (270 Hz) vibration of the fingers 1-3 in 8 healthy subjects. A marked decrease of the amplitude of all potentials was observed. The attenuation of the sensory nerve action potential (SNAP) of the median nerve and the attenuation of SEP components N9, N11 and N13 showed no differences, while the attenuation of the subcortical P14 component was significantly higher. This is in accordance with a generator of the cervical N13 in the interneurons beside the lemniscal pathway. The cortical N20 (post-rolandic) was significantly more decreased in amplitude than P14 while P22 (pre-rolandic) remained reduced in amplitude like P14. An increased latency of the far-field subcortical P14 was observed, while P13 recorded in the same montage remained unchanged in latency. These findings suggest different generators of these peaks. A generator of P14 above the nucleus cuneatus is confirmed. A presynaptic generator of P13 is suspected.
在8名健康受试者中，记录了在手指1-3高频（270Hz）振动前、振动期间和振动后，正中神经刺激诱发的皮层下和皮层体感诱发电位（SEP）。观察到所有电位的幅度均显著下降。正中神经感觉神经动作电位（SNAP）的衰减与SEP成分N9、N11和N13的衰减无差异，而皮层下P14成分的衰减明显更高。这与薄束通路旁中间神经元中颈段N13的发生器一致。皮层N20（中央后回）的幅度下降明显大于P14，而P22（中央前回）的幅度仍像P14一样降低。观察到远场皮层下P14的潜伏期延长，而在相同导联记录的P13潜伏期保持不变。这些发现提示这些波峰有不同的发生器。证实了楔束核上方存在P14的发生器。怀疑P13有一个突触前发生器。
