Henderson R A, Raskino C, Karani S, Sowton E
Department of Cardiology, Guy's Hospital, London, U.K.
Eur Heart J. 1992 Jun;13(6):781-6. doi: 10.1093/oxfordjournals.eurheartj.a060256.
The comparative long-term clinical results of coronary angioplasty in 448 patients with single-vessel and 451 patients with multivessel disease are reported. Clinical status was determined at census for 898 patients (99.9%). Actuarial survival at 5 years was 92.7% for single-vessel and 85.6% for multivessel disease patients (relative risk 2.1). Patients with multivessel disease had higher rates of cardiac death and non-fatal myocardial infarction (relative risk 1.8), and coronary artery bypass surgery (relative risk 2.5) than patients with single-vessel disease. At follow-up 72.6% of single-vessel and 61.3% of multivessel disease patients had no angina and 43.3% and 35.8%, respectively, were taking no regular anti-anginal medication. Treatment by coronary angioplasty is associated with a good long-term prognosis, but survival and event-free survival rates are lower in patients with multivessel disease than in patients with single-vessel disease, even after correction for differences in other baseline characteristics.
报告了448名单支血管病变患者和451名多支血管病变患者冠状动脉血管成形术的长期比较临床结果。对898名患者（99.9%）进行普查以确定临床状况。单支血管病变患者5年精算生存率为92.7%，多支血管病变患者为85.6%（相对风险2.1）。多支血管病变患者的心脏死亡和非致命性心肌梗死发生率（相对风险1.8）以及冠状动脉搭桥手术发生率（相对风险2.5）均高于单支血管病变患者。随访时，72.6%的单支血管病变患者和61.3%的多支血管病变患者无心绞痛，分别有43.3%和35.8%的患者未服用常规抗心绞痛药物。冠状动脉血管成形术治疗具有良好的长期预后，但即使校正其他基线特征差异后，多支血管病变患者的生存率和无事件生存率仍低于单支血管病变患者。
