Zvolensky Michael J, Feldner Matthew T, Leen-Feldner Ellen W, Gibson Laura E, Abrams Kenneth, Gregor Kristin
Department of Psychology, University of Vermont, 320 Dewey Hall, Burlington, VT 05405, USA.
Behav Res Ther. 2005 Dec;43(12):1683-700. doi: 10.1016/j.brat.2004.10.010.
Although previous work has found associations between panic and smoking, little research has investigated potential mechanisms by which smoking may contribute to panic problems. The present investigation evaluated the incremental validity of acute nicotine withdrawal symptoms (elicited by an average of 2h of nicotine deprivation) relative to negative affectivity, anxiety sensitivity, and nicotine dependence in predicting anxiety responding to 3-min voluntary hyperventilation. The sample consisted of 90 regular smokers (46 females), as defined by smoking >or= 10 cigarettes per day for at least 1 year, recruited through the general community. Consistent with prediction, greater levels of pre-challenge nicotine withdrawal symptoms uniquely predicted post-challenge intensity of panic symptoms and anxiety relative to other established factors. Findings are discussed in the context of how regular smoking may promote panic symptomotology.
尽管先前的研究发现惊恐与吸烟之间存在关联，但很少有研究探讨吸烟可能导致惊恐问题的潜在机制。本研究评估了急性尼古丁戒断症状（平均2小时尼古丁剥夺诱发）相对于消极情感性、焦虑敏感性和尼古丁依赖在预测对3分钟自主过度通气的焦虑反应方面的增量效度。样本由90名经常吸烟的人（46名女性）组成，这些人通过社区招募，定义为每天吸烟≥10支且至少持续1年。与预测一致，相对于其他既定因素，更高水平的挑战前尼古丁戒断症状独特地预测了挑战后惊恐症状和焦虑的强度。研究结果在经常吸烟可能如何促进惊恐症状学的背景下进行了讨论。
