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家庭治疗会影响谵妄吗?一项关于老年人居家康复与常规治疗的随机对照试验(REACH-OUT试验)。

Does home treatment affect delirium? A randomised controlled trial of rehabilitation of elderly and care at home or usual treatment (The REACH-OUT trial).

作者信息

Caplan Gideon A, Coconis Janis, Board Neville, Sayers Allyn, Woods Jan

机构信息

Post Acute Care Services, Prince of Wales Hospital, Randwick, Sydney, New South Wales 2031, Australia.

出版信息

Age Ageing. 2006 Jan;35(1):53-60. doi: 10.1093/ageing/afi206. Epub 2005 Oct 20.

Abstract

BACKGROUND

delirium is a frequent adverse consequence of hospitalisation for older patients, but there has been little research into its prevention. A recent study of Hospital in the Home (admission substitution) noted less delirium in the home-treated group.

SETTING

a tertiary referral teaching hospital in Sydney, Australia.

METHODS

we randomised 104 consecutive patients referred for geriatric rehabilitation to be treated in one of two ways, either in Hospital in the Home (early discharge) or in hospital, in a rehabilitation ward. We compared the occurrence of delirium measured by the confusion assessment method. Secondary outcome measures were length of stay, hospital bed days, cost of acute care and rehabilitation, functional independence measure (FIM), Mini-Mental State Examination (MMSE) and geriatric depression score (GDS) assessed on discharge and at 1- and 6-month follow-up and patient satisfaction.

RESULTS

the home group had lower odds of developing delirium during rehabilitation [odds ratio (OR) = 0.17; 95% confidence interval 0.03-0.65], shorter duration of rehabilitation (15.97 versus 23.09 days; P = 0.0164) and used less hospital bed days (20.31 versus 40.09, P < or = 0.0001). The cost was lower for the acute plus rehabilitation phases (7,680 pounds versus 10,598 pounds; P = 0.0109) and the rehabilitation phase alone (2,523 pounds versus 6,100 pounds; P < or = 0.0001). There was no difference in FIM, MMSE or GDS scores. the home group was more satisfied (P = 0.0057).

CONCLUSIONS

home rehabilitation for frail elderly after acute hospitalisation is a viable option for selected patients and is associated with a lower risk of delirium, greater patient satisfaction, lower cost and more efficient hospital bed use.

摘要

背景

谵妄是老年患者住院常见的不良后果,但对其预防的研究较少。最近一项关于居家医院(住院替代模式)的研究指出,居家治疗组的谵妄发生率较低。

地点

澳大利亚悉尼的一家三级转诊教学医院。

方法

我们将104例连续转诊接受老年康复治疗的患者随机分为两组,分别采用居家医院(早期出院)或在医院康复病房两种治疗方式之一。我们通过谵妄评估方法比较谵妄的发生率。次要结局指标包括住院时间、住院天数、急性护理和康复费用、功能独立性测量(FIM)、简易精神状态检查表(MMSE)以及出院时、1个月和6个月随访时评估的老年抑郁量表(GDS)和患者满意度。

结果

居家组在康复期间发生谵妄的几率较低[优势比(OR)=0.17;95%置信区间0.03 - 0.65],康复时间较短(15.97天对23.09天;P = 0.0164),住院天数较少(20.31天对40.09天,P≤0.0001)。急性加康复阶段的费用较低(7680英镑对10598英镑;P = 0.0109),仅康复阶段的费用也较低(2523英镑对6100英镑;P≤0.0001)。FIM、MMSE或GDS评分无差异。居家组更满意(P = 0.0057)。

结论

急性住院后的体弱老年人居家康复对部分患者是一种可行的选择,且与谵妄风险较低、患者满意度更高、成本更低以及医院床位使用更高效相关。

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