Friedman A J, Daly M, Juneau-Norcross M, Fine C, Rein M S
Department of Obstetrics and Gynecology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115.
Fertil Steril. 1992 Jul;58(1):205-8. doi: 10.1016/s0015-0282(16)55164-4.
The recurrence of myomas and myoma-related symptoms was evaluated in women participating in a randomized, double-blind, P-controlled study of the efficacy of LA depot before myomectomy. After 27 to 38 months of follow-up, the recurrence of myomas was found to be greater when at least four myomas were resected. Myoma recurrence was not associated with pretreatment or preoperative uterine volume, resected myoma mass, or preoperative medical therapy.
在接受肌瘤切除术前行左炔诺孕酮长效注射剂疗效的随机、双盲、安慰剂对照研究的女性中，评估了肌瘤复发情况及与肌瘤相关的症状。经过27至38个月的随访，发现切除至少4个肌瘤时肌瘤复发率更高。肌瘤复发与术前治疗或术前子宫体积、切除的肌瘤大小或术前药物治疗无关。
