Nishiwaki H, Kawazoe Y, Yamashita T, Satake K, Sowa M
First Department of Surgery, Osaka City University, Medical School, Japan.
Gastroenterol Jpn. 1992 Jun;27(3):405-10. doi: 10.1007/BF02777761.
A 63-year-old male was admitted to our department for further examination of hypergastrinemia. Secretin provocation test and calcium infusion test suggested Zollinger-Ellison syndrome and percutaneous transhepatic portal venous sampling (PTPVS) demonstrated gastrinoma in the jejunum, although CT, ultrasonography and angiography could not accurately detect the location of the gastrinoma. Laparotomy findings showed a solid tumor 1.5 cm in diameter in the jejunal mesentery 5 cm distal to the ligament of Treitz, and primary gastrinoma was confirmed in the submucosa of the jejunum immediately adjacent to this tumor. An immunohistochemical study using the PAP method revealed gastrin secreting cells in the tumor. In addition to this case of jejunal gastrinoma, a review of literature in Japan and other countries was presented.
一名63岁男性因高胃泌素血症入院进一步检查。促胰液素激发试验和钙输注试验提示卓-艾综合征,经皮经肝门静脉采血(PTPVS)显示空肠存在胃泌素瘤,尽管CT、超声和血管造影无法准确检测胃泌素瘤的位置。剖腹探查结果显示,在屈氏韧带远端5 cm处的空肠系膜中有一个直径1.5 cm的实性肿瘤,紧邻该肿瘤的空肠黏膜下层证实存在原发性胃泌素瘤。使用PAP法进行的免疫组织化学研究显示肿瘤中有胃泌素分泌细胞。除了这例空肠胃泌素瘤病例外,还对日本和其他国家的文献进行了综述。