食管癌诊断中活检标本的最佳数量
Optimal number of biopsy specimens in the diagnosis of carcinoma of the oesophagus.
作者信息
Lal N, Bhasin D K, Malik A K, Gupta N M, Singh K, Mehta S K
机构信息
Department of Internal Medicine, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
出版信息
Gut. 1992 Jun;33(6):724-6. doi: 10.1136/gut.33.6.724.
Abstract
The study evaluated 48 patients with carcinoma of the oesophagus to assess the optimal number of biopsy specimens required to obtain the highest yield. Eight specimens were obtained from each patient and two specimens were placed serially in each of four vials. The first vial provided a positive diagnosis in 95.8% of cases. The addition of two more specimens (second vial) increased the yield to 97.9% and the fifth and sixth specimens increased the positive yield to 100%. There was no statistically significant difference in the yield according to the site and the type of growth.
摘要
该研究评估了48例食管癌患者，以确定获取最高诊断率所需的最佳活检标本数量。每位患者获取8份标本，每份标本分两份依次放入4个小瓶中。第一个小瓶在95.8%的病例中提供了阳性诊断。再增加两份标本（第二个小瓶）使诊断率提高到97.9%，第五和第六份标本使阳性诊断率提高到100%。根据生长部位和类型，诊断率无统计学显著差异。
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