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组织型纤溶酶原激活剂用于急性缺血性卒中:纽约市急诊医学视角

Tissue plasminogen activator for acute ischemic stroke: a New York city emergency medicine perspective.

作者信息

Chan Yu-Feng, Kwiatkowski Thomas G, Rella Joseph G, Rennie William P, Kwon Robert K, Silverman Robert A

机构信息

University of Medicine and Dentistry of New Jersey, Newark, New Jersey 07101, USA.

出版信息

J Emerg Med. 2005 Nov;29(4):405-8. doi: 10.1016/j.jemermed.2005.05.002.

DOI:10.1016/j.jemermed.2005.05.002
PMID:16243196
Abstract

Nationally, only 2-3% of patients with acute ischemic stroke (AIS) currently receive tissue plasminogen activator (TPA). To better understand the reasons, we investigated the practice patterns, level of familiarity and acceptance of TPA for AIS among emergency physicians in New York City (NYC). Fifty-seven 911-receiving hospital emergency department directors were surveyed regarding TPA use. Of those responding, 37% had never used TPA to treat AIS. Lack of neurological support was reported by 33%. Departments with formal protocols were more likely to use TPA for AIS. In conclusion, there is considerable variation in the practice, knowledge, and attitudes regarding the use of TPA for AIS in NYC emergency departments. Improved educational efforts and institutional support may be necessary to ensure the appropriate use of TPA by emergency physicians.

摘要

在全国范围内,目前只有2%至3%的急性缺血性中风(AIS)患者接受组织纤溶酶原激活剂(TPA)治疗。为了更好地了解原因,我们调查了纽约市(NYC)急诊医生对AIS使用TPA的实践模式、熟悉程度和接受程度。对57名接收911急救电话的医院急诊科主任进行了关于TPA使用情况的调查。在做出回应的人中,37%从未使用TPA治疗AIS。33%的人表示缺乏神经科支持。有正式方案的科室更有可能将TPA用于AIS治疗。总之,纽约市急诊科在使用TPA治疗AIS的实践、知识和态度方面存在很大差异。可能需要加强教育力度和机构支持,以确保急诊医生正确使用TPA。

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引用本文的文献

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Neurohospitalist. 2020 Jan;10(1):5-10. doi: 10.1177/1941874419838961. Epub 2019 Apr 14.
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Health professionals' views on the barriers and enablers to evidence-based practice for acute stroke care: a systematic review.医疗专业人员对急性中风护理循证实践的障碍与促进因素的看法:一项系统综述
Implement Sci. 2017 Jun 5;12(1):74. doi: 10.1186/s13012-017-0599-3.
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Pharmaceutical sponsorship bias influences thrombolytic literature in acute ischemic stroke.
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West J Emerg Med. 2011 Nov;12(4):435-41. doi: 10.5811/westjem.2011.5.2166.
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Is the drip-and-ship approach to delivering thrombolysis for acute ischemic stroke safe?对于急性缺血性卒中进行溶栓治疗时采用的“点滴转运”方法是否安全?
J Emerg Med. 2011 Aug;41(2):135-41. doi: 10.1016/j.jemermed.2008.10.018. Epub 2009 Mar 9.