Green B, McDicken I W, Turnbull L S
University Department of Pathology, Liverpool.
J Clin Pathol. 1992 Jun;45(6):521-3. doi: 10.1136/jcp.45.6.521.
To determine whether the recommended methods for the handling of breast excision biopsy specimens from screening patients cause more laboratory work than those used for non-screening patients.
All breast excision biopsy specimens from 1990 were identified. Ninety one came from patients identified during the prevalent round of breast screening. These were compared with 127 from non-screening patients operated on by the same surgeon. The workload in terms of initial blocks taken, cases which needed extra blocks or other additional work, and the time taken for delivery of slides to the pathologist were assessed.
The screening cases required significantly more initial blocks than the non-screening cases (8.03 v 4.95; p = 0.000001). When looking at the malignant diagnoses this difference was maintained (7.74 v 6.02; p = 0.00014).
Excision biopsy specimens from screening patients require more laboratory work per case than those from non-screening patients. The reasons for these differences lie in the nature of the specimens and their subsequent diagnoses, and in the initial indications for biopsy.
确定针对筛查患者乳腺切除活检标本的推荐处理方法是否比用于非筛查患者的方法导致更多的实验室工作。
识别出1990年所有的乳腺切除活检标本。其中91份来自在乳腺筛查流行轮次中确诊的患者。将这些标本与同一位外科医生为非筛查患者进行手术获取的127份标本进行比较。评估了初始取材块数、需要额外取材块或其他额外工作的病例数以及将切片交付给病理学家所需的时间等工作量。
筛查病例所需的初始取材块数显著多于非筛查病例（8.03对4.95；p = 0.000001）。在恶性诊断方面，这种差异依然存在（7.74对6.02；p = 0.00014）。
与非筛查患者的标本相比，筛查患者的切除活检标本每份病例需要更多的实验室工作。这些差异的原因在于标本的性质及其后续诊断，以及活检的初始指征。
