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调强放射治疗作为鼻咽癌的追加或挽救性治疗：逆向计划中的合适参数及患者解剖因素对计划结果的影响

Intensity-modulated radiotherapy as the boost or salvage treatment of nasopharyngeal carcinoma: the appropriate parameters in the inverse planning and the effect of patient's anatomic factors on the planning results.

作者信息

Hsiung Ching-Yeh, Hunt Margie A, Yorke Ellen D, Chui Chen-Shou, Hu Jason, Xiong Jian-Ping, Ling Clifton C, Lo Sing-Kai, Wang Chong-Jong, Huang Eng-Yen, Amols Howard I

机构信息

Department of Radiation Oncology, Chang Gung Memorial Hospital-Kaohsiung, Kaohsiung Hsien, Taiwan, ROC.

出版信息

Radiother Oncol. 2005 Oct;77(1):53-7. doi: 10.1016/j.radonc.2005.04.017.

DOI:10.1016/j.radonc.2005.04.017
PMID:16246743
Abstract

The current study demonstrates that the large increase in normal tissue penalty often degrades target dose uniformity without a concomitant large improvement in normal tissue dose, especially in anatomically unfavorable patients. The excessively large normal tissue penalties do not improve treatment plans for patients having unfavorable geometry.

摘要

当前研究表明，正常组织惩罚的大幅增加常常会降低靶区剂量均匀性，而正常组织剂量却没有随之大幅改善，尤其是在解剖结构不利的患者中。过大的正常组织惩罚并不能改善几何结构不利患者的治疗计划。

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Intensity-modulated radiotherapy as the boost or salvage treatment of nasopharyngeal carcinoma: the appropriate parameters in the inverse planning and the effect of patient's anatomic factors on the planning results.调强放射治疗作为鼻咽癌的追加或挽救性治疗：逆向计划中的合适参数及患者解剖因素对计划结果的影响
Radiother Oncol. 2005 Oct;77(1):53-7. doi: 10.1016/j.radonc.2005.04.017.
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引用本文的文献

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Comparisons of quality of life for patients with nasopharyngeal carcinoma after treatment with different RT technologies.不同放疗技术治疗后鼻咽癌患者生活质量的比较。
Acta Otorhinolaryngol Ital. 2014 Aug;34(4):241-6.
2
MRI-detected skull-base invasion: prognostic value and therapeutic implication in intensity-modulated radiotherapy treatment for nasopharyngeal carcinoma.MRI 检测到的颅底侵犯：调强放疗治疗鼻咽癌的预后价值和治疗意义。
Strahlenther Onkol. 2014 Oct;190(10):905-11. doi: 10.1007/s00066-014-0656-7. Epub 2014 Apr 25.
3
Health-related quality of life in 640 head and neck cancer survivors after radiotherapy using EORTC QLQ-C30 and QLQ-H&N35 questionnaires.
EORTC QLQ-C30 和 QLQ-H&N35 问卷评估放疗后 640 例头颈部癌幸存者的健康相关生活质量。
BMC Cancer. 2011 Apr 12;11:128. doi: 10.1186/1471-2407-11-128.