Slabaugh T K, Ogan K
Department of Urology Emory, University Medical Center, Atlanta, GA 30322, USA.
Minerva Urol Nefrol. 2005 Dec;57(4):261-9.
Nephron sparing surgery has become the gold standard for the treatment of small (< 4 cm) renal tumors. More recently, renal tumor ablation, destroying renal tumors with energy based modalities and leaving the tissue in situ, has gained popularity. Radiofrequency ablation (RFA) utilizes heat energy to cause cellular destruction. RFA can be applied laparoscopically, percutaneously, and as an adjunct with partial nephrectomy. A comprehensive MEDLINE search of the English literature from 1990 to present was performed to identify articles on renal RFA. RFA is an effective minimally invasive treatment alternative for small renal masses in patients with significant comorbidities that preclude extirpative surgery. Limited follow up from a number of series demonstrate a success rate of 92%. RFA has proven to be an effective ablative therapy in a number of organ systems. Over the past decade it has been applied to the treatment of small renal tumors. The short-term efficacy and minimum morbidity of RF thermal therapy for renal tumors has been encouraging. RFA provides a versatile tool to add to the urologist's armamentarium in the minimally invasive treatment of renal cancer.
保留肾单位手术已成为治疗小（<4cm）肾肿瘤的金标准。最近，肾肿瘤消融术，即使用基于能量的方式破坏肾肿瘤并将组织原位保留，越来越受欢迎。射频消融（RFA）利用热能导致细胞破坏。RFA可通过腹腔镜、经皮应用，也可作为部分肾切除术的辅助手段。对1990年至今的英文文献进行了全面的MEDLINE检索，以确定关于肾RFA的文章。对于有严重合并症而无法进行切除手术的患者，RFA是治疗小肾肿块的一种有效的微创治疗选择。多个系列的有限随访显示成功率为92%。RFA已被证明在多个器官系统中是一种有效的消融治疗方法。在过去十年中，它已被应用于小肾肿瘤的治疗。肾肿瘤射频热疗的短期疗效和最低发病率令人鼓舞。RFA为泌尿外科医生在肾癌微创治疗的武器库中增添了一种多功能工具。
