Homo and heterodimers of ddI, d4T and AZT: influence of (5'-5') thiolcabonate-carbamate linkage on anti-HIV activity.
作者信息
Taourirte M, Lazrek H B, Rochdi A, Vasseur J J, Engels J W
机构信息
Faculty of Sciences and Techniques, Marrakech, Morocco.
出版信息
Nucleosides Nucleotides Nucleic Acids. 2005;24(5-7):523-5. doi: 10.1081/ncn-200061793.
PMID:16247983
Abstract
New homo and heterodimers of ddI, d4T and AZT with (5-5) thiolcarbonate-carbamate linkages have been prepared with the aim of testing them against wild type and NNRTI resistant HIV mutants. The prepared dimers showed a low activity in comparison to the parent drug.
摘要
Zotero 插件