Seela Frank, Shaikh Khalil I, Budow Simone, Jawalekar Anup M
Laboratorium für Organische und Bioorganische Chemie, Institut für Chemie, Universität Osnabrück, Germany.
Nucleosides Nucleotides Nucleic Acids. 2005;24(5-7):851-4. doi: 10.1081/ncn-200059184.
Oligonucleotides containing 7-deazapurines or 9-deazapurines with propynyl groups at the 7- or 9-position were prepared. The stabilizing effect of the propynyl group was studied on DNA duplexes, hairpins and triplexes.
制备了在7位或9位带有丙炔基的含7-脱氮嘌呤或9-脱氮嘌呤的寡核苷酸。研究了丙炔基对DNA双链体、发夹结构和三链体的稳定作用。