Juan Yung-Shun, Chuang Shu-Mien, Wu Wen-Jeng, Shen Jung-Tsung, Li Ching-Chia, Wang Chii-Jye, Huang Chun-Hsiung
Department of Urology, Kaohsiung Municipal Hsiao-Kang Hospital, Kaohsiung, Taiwan.
Kaohsiung J Med Sci. 2005 Sep;21(9):412-7. doi: 10.1016/S1607-551X(09)70143-3.
Extracorporeal shock wave lithotripsy (ESWL) is an effective and relatively noninvasive mode of treatment for urinary calculi. The aim of this study was to test whether therapeutic ESWL induces changes in renal parenchymatous blood flow and to evaluate shock wave side effects on the renal parenchyma. A total of 45 patients who underwent ESWL for ureteropelvic stone between January 2002 and July 2003 were included in this prospective study. Color Doppler sonography before and 30 minutes after ESWL showed no significant morphologic change. Resistive index (RI) was used to estimate renovascular resistance. The RI significantly increased in obstructed hydronephrotic kidneys. However, no significant change was observed in both treated and untreated kidneys before and after treatment. Hydronephrotic kidneys do not have a higher risk of post-ESWL renovascular resistance interference. The measurement of changes in RI with Doppler ultrasonography may provide useful information for clinical diagnosis of renal tubulointerstitial and vascular damage.
体外冲击波碎石术（ESWL）是一种治疗尿路结石的有效且相对无创的方法。本研究的目的是测试治疗性ESWL是否会引起肾实质血流变化，并评估冲击波对肾实质的副作用。本前瞻性研究纳入了2002年1月至2003年7月间因输尿管肾盂结石接受ESWL治疗的45例患者。ESWL前及ESWL后30分钟的彩色多普勒超声检查显示无明显形态学变化。阻力指数（RI）用于评估肾血管阻力。梗阻性肾积水肾脏的RI显著升高。然而，治疗前后治疗侧和未治疗侧肾脏均未观察到显著变化。肾积水肾脏在ESWL后发生肾血管阻力干扰的风险并不更高。用多普勒超声测量RI的变化可为肾小管间质和血管损伤的临床诊断提供有用信息。
