Peyrot Mark, Rubin Richard R, Lauritzen Torsten, Skovlund Soren E, Snoek Frank J, Matthews David R, Landgraf Rüdiger, Kleinebreil Line
Department of Sociology, Loyola College, Baltimore, MD 21210-2699, USA.
Diabetes Care. 2005 Nov;28(11):2673-9. doi: 10.2337/diacare.28.11.2673.
To examine the correlates of patient and provider attitudes toward insulin therapy.
Data are from surveys of patients with type 2 diabetes not taking insulin (n = 2,061) and diabetes care providers (nurses = 1,109; physicians = 2,681) in 13 countries in Asia, Australia, Europe, and North America. Multiple regression analysis is used to identify correlates of attitudes toward insulin therapy among patients, physicians, and nurses.
Patient and provider attitudes differ significantly across countries, controlling for individual characteristics. Patients rate the clinical efficacy of insulin as low and would blame themselves if they had to start insulin therapy. Self-blame is significantly lower among those who have better diet and exercise adherence and less diabetes-related distress. Patients who are not managing their diabetes well (poor perceived control, more complications, and diabetes-related distress) are significantly more likely to see insulin therapy as potentially beneficial. Most nurses and general practitioners (50-55%) delay insulin therapy until absolutely necessary, but specialists and opinion leaders are less likely to do so. Delay of insulin therapy is significantly less likely when physicians and nurses see their patients as more adherent to medication or appointment regimens, view insulin as more efficacious, and when they are less likely to delay oral diabetes medications.
Patient and provider resistance to insulin therapy is substantial, and for providers it is part of a larger pattern of reluctance to prescribe blood glucose-lowering medication. Interventions to facilitate timely initiation of insulin therapy will need to address factors associated with this resistance.
研究患者及医疗服务提供者对胰岛素治疗态度的相关因素。
数据来自对亚洲、澳大利亚、欧洲和北美的13个国家中未使用胰岛素的2型糖尿病患者(n = 2061)以及糖尿病护理人员(护士 = 1109;医生 = 2681)的调查。采用多元回归分析来确定患者、医生和护士对胰岛素治疗态度的相关因素。
在控制个体特征后,不同国家的患者和医疗服务提供者的态度存在显著差异。患者对胰岛素的临床疗效评价较低,并且如果不得不开始胰岛素治疗会自责。在饮食和运动依从性较好且糖尿病相关困扰较少的人群中,自责程度明显较低。糖尿病管理不佳(自我感觉控制差、并发症多以及糖尿病相关困扰多)的患者更有可能认为胰岛素治疗可能有益。大多数护士和全科医生(50 - 55%)会将胰岛素治疗推迟到绝对必要时,但专科医生和意见领袖则较少这样做。当医生和护士认为患者对药物治疗或预约方案的依从性更高、认为胰岛素更有效以及不太可能推迟口服降糖药时,推迟胰岛素治疗的可能性显著降低。
患者和医疗服务提供者对胰岛素治疗存在较大抵触,对医疗服务提供者而言,这是不愿开具降糖药物这一更大模式的一部分。促进及时开始胰岛素治疗的干预措施需要解决与这种抵触相关的因素。