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[儿童期囊性纤维化与葡萄膜炎及成年期多发性硬化症]

[Cystic fibrosis and uveitis in childhood and multiple sclerosis at adulthood].

作者信息

Baudet D, Minot-Myhie M-C, Guyomard J-L, Vanhaecke F, Edan G, Charlin J-F

机构信息

Service d'Ophtalmologie, Centre Hospitalier Universitaire, Hôpital Pontchaillou, Rennes.

出版信息

J Fr Ophtalmol. 2005 Oct;28(8):850-3. doi: 10.1016/s0181-5512(05)81004-6.

Abstract

We report the case of a patient with cystic fibrosis who suffered severe bilateral uveitis, with hypopyon, retinal vasculitis, and polyarthritis when he was 6 years old. No etiology could be found. Multiple sclerosis began when he was 22 years old. This panuveitis was clinically very different from the uveitis usually associated with multiple sclerosis. Polyarthritis and skin vasculitis have been reported in the course of cystic fibrosis, but no uveitis nor retinal vasculitis have been described. This raises the question of the role of multiple sclerosis and cystic fibrosis in the pathogenesis of this case of uveitis.

摘要

我们报告了一例囊性纤维化患者的病例,该患者6岁时患严重双侧葡萄膜炎,伴有前房积脓、视网膜血管炎和多关节炎。未发现病因。22岁时开始出现多发性硬化症。这种全葡萄膜炎在临床上与通常与多发性硬化症相关的葡萄膜炎有很大不同。在囊性纤维化病程中曾有过关于多关节炎和皮肤血管炎的报道,但未描述过葡萄膜炎和视网膜血管炎。这就引发了关于多发性硬化症和囊性纤维化在该例葡萄膜炎发病机制中作用的问题。

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