Rogues A-M, Dumartin C, Parneix P, Prudhon H, Placet-Thomazeau B, Beneteau C, Dosque J-P, Marty N, Labadie J-C, Gachie J-P
Unité Inserm 657, pharmacoépidémiologie et évaluation de l'impact des produits de santé sur les populations, université Victor-Segalen-Bordeaux-II, France.
Med Mal Infect. 2005 Nov;35(11):536-42. doi: 10.1016/j.medmal.2005.09.004. Epub 2005 Oct 25.
Increasing antimicrobial resistance in bacteria is a major health problem and requires the implementation of stringent policies to optimize the use of antibiotics.
In 2003 the authors conducted a study in southwestern French hospitals, using a questionnaire to assess the implementation of antibiotic policies according to national guidelines issued by the French government in 2002.
The most frequent actions quoted by the 99 respondents were: issuing of a list of available antibiotics, issuing of information regarding antibiotic consumption and bacterial resistance, and control of antibiotics dispensation. Local guidelines were available in 45% of hospitals for curative treatment and in 87% for antibioprophylaxis in surgery. The evaluation of antibiotic use and computer links between clinical settings, pharmacy and microbiology lab were the less widespread measures. The number and type of actions were related to hospital size and activity.
These findings support that policies for an appropriate use of antimicrobials should be reinforced by issuing treatment guidelines and specific tools for dispensation and evaluation. This survey also emphasizes the need for appropriate policies relating to the size and medical activities of healthcare institutions.
细菌耐药性不断增加是一个重大的健康问题,需要实施严格政策以优化抗生素的使用。
2003年,作者在法国西南部的医院开展了一项研究,使用问卷调查来评估根据法国政府2002年发布的国家指南实施抗生素政策的情况。
99名受访者提及的最常见措施包括:发布可用抗生素清单、发布有关抗生素使用和细菌耐药性的信息以及控制抗生素配给。45%的医院有针对治疗的本地指南,87%的医院有针对手术中抗生素预防的本地指南。对抗生素使用的评估以及临床科室、药房和微生物实验室之间的计算机连接是普及程度较低的措施。措施的数量和类型与医院规模和业务活动有关。
这些发现支持应通过发布治疗指南以及配给和评估的具体工具来加强合理使用抗菌药物的政策。这项调查还强调了针对医疗机构规模和医疗活动制定适当政策的必要性。