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在比利时医院实施全国范围的抗生素管理团队:一项自我报告调查。

Nationwide implementation of antibiotic management teams in Belgian hospitals: a self-reporting survey.

机构信息

Belgian Antibiotic Policy Coordination Committee (BAPCOC), Federal Public Service Health, Food Chain Safety and Environment, Victor Horta plein 40/10, 1060 Brussels, Belgium.

出版信息

J Antimicrob Chemother. 2010 Mar;65(3):576-80. doi: 10.1093/jac/dkp470. Epub 2010 Jan 6.

DOI:10.1093/jac/dkp470
PMID:20053695
Abstract

OBJECTIVES

Antibiotic management teams (AMTs) have been advocated to optimize the use of antimicrobials in hospitals. Since 2002, the Belgian Antibiotic Policy Coordination Committee (BAPCOC) has supported the development of AMTs in Belgian hospitals with policy guidance and federal funding for antibiotic managers. We performed a national, self-reporting survey to assess the level of AMT activities in 2007.

METHODS

A structured questionnaire survey was performed on the composition, organization and service activities of the AMT in all acute care and larger chronic care hospitals in the country in 2007. Descriptive statistics were stratified by duration of AMT funding.

RESULTS

Completed questionnaires were provided by 112 of 116 hospitals (response rate, 96.6%). Mutidisciplinary AMTs varied in size (mean 10, range 2-28 members). Antibiotic stewardship tools used by AMTs included: hospital antibiotic formulary (96.3% of hospitals); practice guidelines for antibiotic therapy and surgical prophylaxis (91.6% and 96.3%, respectively); list of 'restricted' antimicrobial agents (75.9%); concurrent review of antibiotic therapies (64.2%); de-escalation of therapy after a few days (63.9%); sequential intravenous/oral therapy for antibiotics with equivalent bioavailability (78.7%); dedicated antimicrobial order forms (36.1%); automatic stop of delivery (43.5%); analysis of antibiotic consumption data (96.2%); and analysis of microbial resistance data (89.8%).

CONCLUSIONS

These data demonstrate a well-developed structure of AMTs in Belgian hospitals and the broad range of services provided. Technical and financial support by healthcare authorities was key to the extensive implementation of antimicrobial stewardship programmes across the national hospital care system.

摘要

目的

抗生素管理团队(AMT)已被倡导用于优化医院的抗生素使用。自 2002 年以来,比利时抗生素政策协调委员会(BAPCOC)通过政策指导和为抗生素管理者提供联邦资金,支持比利时医院开发 AMT。我们进行了一项全国性的自我报告调查,以评估 2007 年 AMT 活动的水平。

方法

2007 年,对全国所有急性护理和较大慢性护理医院的 AMT 的组成、组织和服务活动进行了结构化问卷调查。按 AMT 资金使用期限进行描述性统计分析。

结果

116 家医院中的 112 家(响应率为 96.6%)提供了完成的调查问卷。多学科 AMT 的规模各不相同(平均 10 人,范围 2-28 人)。AMT 使用的抗生素管理工具包括:医院抗生素处方集(96.3%的医院);抗生素治疗和手术预防用药实践指南(分别为 91.6%和 96.3%);“限制”抗菌药物清单(75.9%);同时审查抗生素治疗(64.2%);在数天后降低治疗强度(63.9%);具有等效生物利用度的抗生素序贯静脉/口服治疗(78.7%);专用抗菌药物医嘱单(36.1%);自动停止输送(43.5%);抗生素使用数据分析(96.2%);和微生物耐药数据分析(89.8%)。

结论

这些数据表明,比利时医院的 AMT 结构完善,提供的服务范围广泛。医疗保健当局的技术和财务支持是在全国医院护理系统中广泛实施抗菌药物管理计划的关键。

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