Quigley F, Greene M, O'Connor D, Kelly F
Oakacre, Ballineen, Co Cork.
Ir Med J. 2005 Sep;98(8):232-5.
CRY (Cardiac Risk in the Young) is a registered Irish charity established by parents who are bereaved as a result of sudden cardiac death. The aim of this study is to establish the incidence and causes of sudden cardiac death in Dublin city in the 10-year period from 1st January 1993 to 31st December 2002. All sudden cardiac deaths in the under 35-year age group which were reported to the city coroner in the study period were examined. Details regarding age, sex, previous symptoms, investigations, circumstances of death and main pathological finding were recorded in each case. A total of 72 cases of sudden cardiac death in the under-35 year age group were reported. 52 were men. The median age was 26.5 years (range 12-34 years). The cause of death in 20 cases was reported as atherosclerotic Coronary Artery Disease. The second commonest cause of death (24% cases) was Hypertrophic Cardiomyopathy. Hypertrophic Cardiomyopathy was the commonest cause of death under the age of 25 years. Overall atherosclerotic coronary artery disease was the commonest cause of death in this group. The importance of Hypertrophic Cardiomyopathy is highlighted by the fact it was the commonest cause of death in the under 25-year age group. Screening those at high risk of sudden cardiac death especially the relatives of those affected by Hypertrophic Cardiomyopathy need to be discussed and implemented.
CRY（青年心脏风险组织）是一家在爱尔兰注册的慈善机构，由因心源性猝死而痛失亲人的父母们创立。本研究的目的是确定1993年1月1日至2002年12月31日这10年间都柏林市心源性猝死的发病率及病因。对研究期间向市验尸官报告的所有35岁以下心源性猝死病例进行了检查。记录了每个病例的年龄、性别、既往症状、检查情况、死亡情形及主要病理发现的详细信息。共报告了72例35岁以下心源性猝死病例。其中52例为男性。中位年龄为26.5岁（范围12 - 34岁）。20例的死因报告为动脉粥样硬化性冠状动脉疾病。第二大常见死因（占病例的24%）是肥厚型心肌病。肥厚型心肌病是25岁以下人群最常见的死因。总体而言，动脉粥样硬化性冠状动脉疾病是该组最常见的死因。肥厚型心肌病作为25岁以下人群最常见的死因这一事实凸显了其重要性。需要讨论并实施对心源性猝死高危人群的筛查，尤其是肥厚型心肌病患者亲属的筛查。
