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[德国膀胱癌的临床试验]

[Clinical trials for bladder cancer in Germany].

作者信息

Lehmann J, Böhle A

机构信息

Klinik für Urologie und Kinderurologie, Universitätsklinikum des Saarlandes, Homburg/Saar.

出版信息

Urologe A. 2005 Dec;44(12):1435-8. doi: 10.1007/s00120-005-0942-1.

Abstract

The urothelial cancer section of the Association of Urogenital Oncology (AUO) of the German Cancer Society has successfully performed and published clinical trials on treatment of urothelial neoplasia. During the last decade, around 770 patients have been recruited for several phase I, II and III trials. The majority of trials had been conceived for advanced inoperable stages, but the AUO has also been particularly successful in recruiting large trials on adjuvant chemotherapy after radical cystectomy for locally advanced bladder cancer. Future goals address extending the number of active centers in Germany as well as seeking international collaborations in order to enable timely recruitment of trials that demand an extensive sample size.

摘要

德国癌症协会泌尿生殖肿瘤学会(AUO)的尿路上皮癌研究组已成功开展并发表了关于尿路上皮肿瘤治疗的临床试验。在过去十年中,约770名患者被纳入多项I期、II期和III期试验。大多数试验针对的是无法手术的晚期阶段,但AUO在招募针对局部晚期膀胱癌根治性膀胱切除术后辅助化疗的大型试验方面也尤为成功。未来的目标是增加德国活跃中心的数量,并寻求国际合作,以便能够及时招募需要大量样本量的试验。

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