Hama Yukihiro, Yakushiji Tadayuki, Iwasaki Yoshie, Kaji Tatsumi, Isomura Naoei, Kusano Shoichi
Radiation Biology Branch, National Cancer Institute, NIH, Building 10, Room B3B69, Bethesda, MD 20892 USA.
Yonsei Med J. 2005 Oct 31;46(5):733-6. doi: 10.3349/ymj.2005.46.5.733.
Pulmonary embolism (PE) is a common disease with a high mortality rate due to right ventricular dysfunction and underfilling of the left ventricle. We present a case of a 33-year-old man with hemodynamically compromised massive PE. His left atrium was collapsed with marked dilatation of the right atrium and ventricle on multi-detector-row CT scans. The patient was treated with an intracatheter injection of a mutant tissue-type plasminogen activator and subsequently showed clinical and radiological improvements. The small left atrial size in combination with a right ventricular pressure overload was considered to be an adjunctive sign of hemodynamically compromised massive PE.
肺栓塞(PE)是一种常见疾病,由于右心室功能障碍和左心室充盈不足,死亡率很高。我们报告一例33岁男性血流动力学受损的大面积肺栓塞病例。多排探测器CT扫描显示其左心房塌陷,右心房和右心室明显扩张。该患者接受了经导管注射突变型组织型纤溶酶原激活剂治疗,随后临床和影像学表现均有改善。左心房较小并伴有右心室压力过载被认为是血流动力学受损的大面积肺栓塞的一个辅助征象。