Guo Xue-rong, Zhou Yi-wu, Ma Yi-lie
Faculty of Forensic Medicine, Huazhong University of Science & Technology, Wuhan 430030, China.
Fa Yi Xue Za Zhi. 2005 Aug;21(3):223-5.
Cyclooxygenase (COX) is the obligate, rate-limiting enzyme for the conversion of arachidonic acid into prostaglandins, which mediate mitogenesis, apoptosis, angiogenesis, blood flow, secondary injury, and inflammation. COX is consist of 2 subtypes: COX-1 and COX-2. In recent years, there are a number of lines of evidence that COX-1 and COX-2 play a important in role brain injuries.
