通过在空气-水界面的外消旋二维微晶中的不对称诱导产生的同手性寡肽；长链两亲性α-氨基酸的乙酯/硫代乙酯体系。

Homochiral oligopeptides generated via an asymmetric induction in racemic 2D crystallites at the air-water interface; the system ethyl/thio-ethyl esters of long-chain amphiphilic alpha-amino acids.

作者信息

Rubinstein Irina, Kjaer Kristian, Weissbuch Isabelle, Lahav Meir

机构信息

Department of Material and Interfaces, The Weizmann Institute of Science, 76100-Rehovot, Israel.

出版信息

Chem Commun (Camb). 2005 Nov 21(43):5432-4. doi: 10.1039/b507457f. Epub 2005 Sep 30.

DOI:10.1039/b507457f

PMID:16261237

Abstract

N(epsilon)-stearoyl-lysine-ethyl-ester (C18-OE-Lys) operates as an efficient desymmetrizing agent for the generation of homochiral oligopeptides via a reaction catalyzed by silver ions in two-dimensional (2D) quasi-racemic crystallites of the corresponding thio-ester (C18-TE-Lys) self-assembled on water.

摘要

N（ε）-硬脂酰赖氨酸乙酯（C18-OE-Lys）作为一种高效的去对称化试剂，可通过银离子催化的反应，在水相中自组装的相应硫酯（C18-TE-Lys）的二维（2D）准外消旋微晶中生成同手性寡肽。